Literature DB >> 19860752

Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy.

M Brenni1, M Worn, M Brüesch, D R Spahn, M T Ganter.   

Abstract

Transfusion of allogeneic blood products is associated with increased morbidity and mortality. Therefore, strategies for reducing transfusion of these products during trauma management are valuable. We report a case of severe blunt abdominal trauma, successfully treated with antifibrinolytic medication and fibrinogen concentrate. Rotational thromboelastometry (ROTEM) was used to identify hyperfibrinolysis and afibrinogenaemia. In order to achieve haemostasis, over a 3-h period, the patient received a total of 1 g of tranexamic acid, 7 U of packed red blood cells, 16 g of fibrinogen concentrate (Haemocomplettan P), 3500 ml of colloids and 5500 ml of lactated Ringer's solution. Together with surgical measures, this treatment stopped the bleeding and stabilised the patient. There was no transfusion of either fresh-frozen plasma or platelets. The limited need for allogeneic blood products is of particular interest, and clinical studies of the approach used here appear to be warranted.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19860752     DOI: 10.1111/j.1399-6576.2009.02132.x

Source DB:  PubMed          Journal:  Acta Anaesthesiol Scand        ISSN: 0001-5172            Impact factor:   2.105


  14 in total

1.  Avoiding blood transfusion in surgical patients (including Jehovah’s Witnesses).

Authors:  M S Gohel; R A Bulbulia; K R Poskitt; M R Whyman
Journal:  Ann R Coll Surg Engl       Date:  2011-09       Impact factor: 1.891

2.  What's new in hemorrhagic shock?

Authors:  Krisztián Tánczos; Márton Németh; Zsolt Molnár
Journal:  Intensive Care Med       Date:  2015-01-22       Impact factor: 17.440

Review 3.  Fibrinolysis in trauma: a review.

Authors:  M J Madurska; K A Sachse; J O Jansen; T E Rasmussen; J J Morrison
Journal:  Eur J Trauma Emerg Surg       Date:  2017-09-16       Impact factor: 3.693

4.  Thromboelastography values from pigtail macaques ( Macaca nemestrina): effects of age and sex.

Authors:  Derek L Fong; James C Ha; Charlotte E Hotchkiss
Journal:  J Am Assoc Lab Anim Sci       Date:  2012-01       Impact factor: 1.232

Review 5.  Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Authors:  Donat R Spahn; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Rolf Rossaint
Journal:  Crit Care       Date:  2013-04-19       Impact factor: 9.097

6.  The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition.

Authors:  Rolf Rossaint; Bertil Bouillon; Vladimir Cerny; Timothy J Coats; Jacques Duranteau; Enrique Fernández-Mondéjar; Daniela Filipescu; Beverley J Hunt; Radko Komadina; Giuseppe Nardi; Edmund A M Neugebauer; Yves Ozier; Louis Riddez; Arthur Schultz; Jean-Louis Vincent; Donat R Spahn
Journal:  Crit Care       Date:  2016-04-12       Impact factor: 9.097

7.  Functional definition and characterization of acute traumatic coagulopathy.

Authors:  Ross Davenport; Joanna Manson; Henry De'Ath; Sean Platton; Amy Coates; Shubha Allard; Daniel Hart; Rupert Pearse; K John Pasi; Peter MacCallum; Simon Stanworth; Karim Brohi
Journal:  Crit Care Med       Date:  2011-12       Impact factor: 7.598

8.  Trends in trauma transfusion.

Authors:  Sanjay M Bhananker; Ramesh Ramaiah
Journal:  Int J Crit Illn Inj Sci       Date:  2011-01

Review 9.  Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review.

Authors:  Sibylle Kozek-Langenecker; Benny Sørensen; John R Hess; Donat R Spahn
Journal:  Crit Care       Date:  2011-10-14       Impact factor: 9.097

10.  Resuscitative strategies in traumatic hemorrhagic shock.

Authors:  Adrien Bouglé; Anatole Harrois; Jacques Duranteau
Journal:  Ann Intensive Care       Date:  2013-01-12       Impact factor: 6.925

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.