| Literature DB >> 19860384 |
Lutz F Tietze1, Nina Tölle, Daniel Kratzert, Dietmar Stalke.
Abstract
A domino process consisting of an amidation, spirocyclization, and formation of an iminium ion and electrophilic aromatic substitution of a phenylethylamine and a ketoester leads to the spirocyclic skeleton of (+)-erysotramidine, which can be further transformed into the natural alkaloid.Entities:
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Year: 2009 PMID： 19860384 DOI： 10.1021/ol901980u
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005