Literature DB >> 19859016

Chagas disease as a cause of symptomatic chronic myocardopathy in Mexican children.

Paz Maria Salazar-Schettino1, Rafael Perera, Adela Luisa Ruiz-Hernandez, Martha Irene Bucio Torres, Carlos Zamora-Gonzalez, Margarita Cabrera-Bravo, Anthony Harnden.   

Abstract

We report the first case series of children in Mexico living with symptomatic Chagas disease causing chronic myocardopathy. The findings suggest that children with Chagas disease may develop symptomatic chronic myocardopathy earlier than previously recognized. Our findings emphasize the importance of longitudinal cardiologic follow-up of all children identified with acute Chagas disease.In a cohort of 826 children from the state of Queretaro in Mexico, 11 were identified with positive serology (ELISA and IFI) for Chagas and were tested for electrocardiogram alterations and symptoms and signs. Four children had ECG alterations with 3 of these reporting signs and symptoms associated with the chronic phase of Chagas disease (27%; 95% CI: 6%-61%). The most common chronic symptom was chest pain, with one child also reporting dyspnea and tachycardia.

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Year:  2009        PMID: 19859016     DOI: 10.1097/INF.0b013e3181ad8425

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  3 in total

1.  Follow-up of an asymptomatic Chagas disease population of children after treatment with nifurtimox (Lampit) in a sylvatic endemic transmission area of Colombia.

Authors:  Fiorella Bianchi; Zulma Cucunubá; Felipe Guhl; Nadia Lorena González; Hector Freilij; Rubén Santiago Nicholls; Juan David Ramírez; Marleny Montilla; Astrid Carolina Flórez; Fernando Rosas; Victor Saavedra; Nubia Silva
Journal:  PLoS Negl Trop Dis       Date:  2015-02-27

2.  Electrocardiographic Abnormalities and Treatment with Benznidazole among Children with Chronic Infection by Trypanosoma cruzi: A Retrospective Cohort Study.

Authors:  Lisandro D Colantonio; Nilda Prado; Elsa L Segura; Sergio Sosa-Estani
Journal:  PLoS Negl Trop Dis       Date:  2016-05-09

3.  Acute Pediatric Chagas Disease in Antioquia, Colombia: A Geographic Location of Suspected Oral Transmission.

Authors:  Lídia Gual-Gonzalez; Catalina Arango-Ferreira; Laura Camila Lopera-Restrepo; Omar Cantillo-Barraza; Daniela Velásquez Marín; Natalia Restrepo Bustamante; Omar Triana-Chavez; Melissa S Nolan
Journal:  Microorganisms       Date:  2021-12-22
  3 in total

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