| Literature DB >> 19858772 |
Thanyawee Puthanakit1, Kulkanya Chokephaibulkit, Piyarat Suntarattiwong, Meena Gorowara, Pimsiri Leawsrisuk, Tulathip Suwanlerk, Pitch Boonrak, Kiat Ruxrungtham.
Abstract
Because of the lack of a lopinavir/ritonavir (LPV/r) pediatric formulation, 54 HIV-infected children were given generic LPV/r adult tablets. Of 54 children, 21 took cut pills to get the appropriate dose. The median (interquartile range) LPV trough serum concentration (C trough) was 6.7 (5.0-9.9) mg/L. All the children had C trough >1.0 mg/L and 96% had values >4.0 mg/L. LPV/r adult tablets can be used in children when it is necessary.Entities:
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Year: 2010 PMID： 19858772 DOI： 10.1097/INF.0b013e3181b21040
Source DB: PubMed Journal: Pediatr Infect Dis J ISSN： 0891-3668 Impact factor: 2.129