Literature DB >> 19858697

Thoracoscopic removal of mediastinal parathyroid glands: a critical appraisal of an emerging technique.

Bruto Randone1, Renato Costi, Olivier Scatton, Yvonne Fulla, Xavier Bertagna, Olivier Soubrane, Philippe Bonnichon.   

Abstract

OBJECTIVE: To retrospectively evaluate the feasibility of thoracoscopic removal of mediastinal parathyroids. SUMMARY BACKGROUND DATA: Mediastinal exploration to resect ectopic parathyroid(s) is needed in approximately 2% of cases in hyperparathyroidism. Recent advances in thoracoscopic surgery allow for a minimally invasive treatment.
METHODS: From 1999 through 2007, 13 patients affected by primary hyperparathyroidism (11 females, mean age 60 years, range: 22-88) underwent thoracoscopic removal of mediastinal parathyroids. Scintigraphy produced positive results in 11 of 13 cases, computed tomography scan in 9 of 10, parathyroid hormone venous sampling in 10 of 10 patients, and magnetic resonance imaging in 5 of 7. Right thoracoscopic access was used in 9 patients, left in 4. Postoperative outcome was analyzed.
RESULTS: Thoracoscopy enabled retrieval of mediastinal parathyroids in 10 of 13 (78%) cases. Mean operating time was 92 minutes (range: 50-240). One procedure (8%) was converted. No perioperative deaths/major complications occurred. Mild complications occurred in 2 of 13 (15%) patients (pneumothorax/pneumonia, transient recurrent nerve palsy). Mean hospital stay was 4.7 days (range: 2-15). At a mean follow-up of 73 months (range: 16-105), parathyroid hormone and calcium venous concentrations were high in 3 patients. Unsuccessful procedures were related to doubtful or non-concordant preoperative localization.
CONCLUSIONS: The thoracoscopic approach for mediastinal parathyroidectomy is feasible and safe. An accurate preoperative work-up should be standardized to avoid useless procedures. In case of negative preoperative localization of the abnormal gland, thoracoscopy should not be adopted as a diagnostic tool.

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Year:  2010        PMID: 19858697     DOI: 10.1097/SLA.0b013e3181c1cfb0

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  14 in total

Review 1.  [Intraoperative parathyroid hormone determination for primary hyperparathyroidism].

Authors:  K Lorenz; H Dralle
Journal:  Chirurg       Date:  2010-07       Impact factor: 0.955

2.  The results of surgery for mediastinal parathyroid tumors: a comparative study of 63 patients.

Authors:  Maurizio Iacobone; Isabella Mondi; Giovanni Viel; Marilisa Citton; Saveria Tropea; Mauro Frego; Gennaro Favia
Journal:  Langenbecks Arch Surg       Date:  2010-07-10       Impact factor: 3.445

3.  Prevertebral cervical approach: a pure endoscopic surgical technique for posterior mediastinum parathyroid adenomas.

Authors:  Juan Manuel Martos-Martínez; Cristina Sacristán-Pérez; Marina Pérez-Andrés; Virginia María Durán-Muñoz-Cruzado; Verónica Pino-Díaz; Francisco Javier Padillo-Ruiz
Journal:  Surg Endosc       Date:  2016-08-23       Impact factor: 4.584

4.  Comparison of the perioperative outcomes in antero-superior mediastinal tumor resection performed by transcervical resection and video-assisted thoracoscopic surgery.

Authors:  Xin-Sheng Zhu; Nan Song; Nai-Cheng Song; Alan Dart Loon Sihoe; Wen-Xin He; Ming Liu; Ge-Ning Jiang; Peng Zhang
Journal:  J Thorac Dis       Date:  2018-12       Impact factor: 2.895

5.  Focused approach to ectopic mediastinal parathyroid surgery assisted by radio-guided navigation.

Authors:  Naoyoshi Onoda; Tetsuro Ishikawa; Noritoshi Nishiyama; Joji Kawabe; Tsutomu Takashima; Kosei Hirakawa
Journal:  Surg Today       Date:  2013-03-15       Impact factor: 2.549

Review 6.  Endoscopic and robotic parathyroidectomy in patients with primary hyperparathyroidism.

Authors:  Laurent Brunaud; Zhen Li; Klaas Van Den Heede; Thomas Cuny; Sam Van Slycke
Journal:  Gland Surg       Date:  2016-06

Review 7.  Mediastinal parathyroid adenomas and their surgical implications.

Authors:  Jesse Hu; K Y Ngiam; R Parameswaran
Journal:  Ann R Coll Surg Engl       Date:  2015-05       Impact factor: 1.891

8.  Thoracoscopic removal of hypertrophic mediastinal parathyroid glands in recurrent secondary hyperparathyroidism.

Authors:  Hung-I Lu; Fong-Fu Chou; Shun-Yu Chi; Shun-Chen Huang
Journal:  World J Surg       Date:  2015-02       Impact factor: 3.352

9.  High cardiac background activity limits 99mTc-MIBI radioguided surgery in aortopulmonary window parathyroid adenomas.

Authors:  Thomas Schwarzlmüller; Katrin Brauckhoff; Kristian Løvås; Martin Biermann; Michael Brauckhoff
Journal:  BMC Surg       Date:  2014-04-23       Impact factor: 2.102

10.  Gamma probe-assisted excision of an ectopic parathyroid adenoma located within the thymus: case report and review of the literature.

Authors:  Stavros I Daliakopoulos; George Chatzoulis; Savvas Lampridis; Varvara Pantelidou; Omiros Zografos; Konstantinos Ioannidis; Michael Sapranidis; Avraam Ploumis
Journal:  J Cardiothorac Surg       Date:  2014-03-31       Impact factor: 1.637

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