| Literature DB >> 19857492 |
Mathieu Sarasa1, Luisa Rambozzi, Luca Rossi, Pier G Meneguz, Emmanuel Serrano, José-Enrique Granados, Francisco J González, Paulino Fandos, Ramón C Soriguer, Georges Gonzalez, Jean Joachim, Jesús M Pérez.
Abstract
Host acquired immunity is a critical factor that conditions the survival of parasites. Nevertheless, there is a shortage of data concerning inter-individual immunological inequalities in wild mammals. Sarcoptic mange is a widespread parasitosis that severely affects mammals such as the Iberian ibex (Capra pyrenaica). Despite some work on the subject, the immune response to sarcoptic mange infestation is still a complex and poorly understood phenomenon. To improve knowledge of the host-Sarcoptes immunological interaction, 18 Iberian ibexes were experimentally infested. IgG levels were assessed using ELISA to test for potential factors determining the specific immune response to infestation. Previous exposure and sex appeared to affect the IgG response to infestation and our results suggest a sex-biased immunomodulation. We discuss the immunological pattern of host-Sarcoptes interactions and also suggest further lines of work that may improve the understanding of immunological interactions of host-Sarcoptes systems. Copyright 2009 Elsevier Inc. All rights reserved.Entities:
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Year: 2009 PMID： 19857492 DOI： 10.1016/j.exppara.2009.10.008
Source DB: PubMed Journal: Exp Parasitol ISSN： 0014-4894 Impact factor: 2.011