Literature DB >> 19856926

A Pd-catalyzed heteroannulation approach to 2,3-disubstituted furo[3,2-c]coumarins.

Guillaume Raffa1, Marion Rusch, Geneviève Balme, Nuno Monteiro.   

Abstract

The Pd-catalyzed cyclofunctionalization of 3-alkynyl-4-methoxycoumarins with aryl halides resulted in the selective formation of 3-arylfuro[3,2-c]coumarins in lieu of the expected regioisomeric 3-arylfuro[2,3-b]chromones. A mechanism involving the linear to angular rearrangement of a Pd-containing furan intermediate was proposed.

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Year:  2009        PMID： 19856926     DOI： 10.1021/ol902189q

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Expeditious entry to novel 2-methylene-2,3-dihydrofuro[3,2-c] chromen-2-ones from 6-chloro-4-hydroxychromen-2-one and propargylic alcohols.

Authors:  Noel Nebra; Alba E Díaz-Álvarez; Josefina Díez; Victorio Cadierno
Journal:  Molecules       Date:  2011-08-02       Impact factor: 4.411

Review 2.  Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part 1: Five-Membered Aromatic Rings with One Heteroatom.

Authors:  Eslam Reda El-Sawy; Ahmed Bakr Abdelwahab; Gilbert Kirsch
Journal:  Molecules       Date:  2021-01-18       Impact factor: 4.411

Review 3.  Furo[3,2-c]coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms.

Authors:  Iván Cortés; L Javier Cala; Andrea B J Bracca; Teodoro S Kaufman
Journal:  RSC Adv       Date:  2020-09-10       Impact factor: 4.036
  3 in total

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