Literature DB >> 19856925

Oxazaborolidinone-catalyzed enantioselective Friedel-Crafts alkylation of furans and indoles with alpha,beta-unsaturated ketones.

Shinya Adachi1, Fumi Tanaka, Kazuya Watanabe, Toshiro Harada.   

Abstract

allo-Threonine-derived oxazaborolidinone (10 mol %) catalyzes the Friedel-Crafts alkylation of furans and indoles with simple acyclic alpha,beta-unsaturated ketones to give products with high yield and high enantioselectivity. The use of N,N-dimethylaniline (2.5-10 mol %) as an additive is essential for enantioselectivity.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19856925     DOI： 10.1021/ol9021436

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds.

Authors:  Aurélie Moniot; Julien Braux; Renaud Siboni; Christine Guillaume; Sandra Audonnet; Ingrid Allart-Simon; Janos Sapi; Rabindra Tirouvanziam; Stéphane Gérard; Sophie C Gangloff; Frédéric Velard
Journal:  Int J Mol Sci       Date:  2022-06-29       Impact factor: 6.208

2.  Pyridazinone Derivatives Limit Osteosarcoma-Cells Growth In Vitro and In Vivo.

Authors:  Aurélie Moniot; Julien Braux; Camille Bour; Christine Guillaume; Fabien Lamret; Ingrid Allart-Simon; Sandra Audonnet; Sarah Renault; Francoise Rédini; Marie Laronze-Cochard; Janos Sapi; Sophie C Gangloff; Stéphane Gérard; Frédéric Velard
Journal:  Cancers (Basel)       Date:  2021-11-28       Impact factor: 6.639
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.