Literature DB >> 19856888

[Clinical significance of some genetic polymorphisms of cytochrome P-450 subfamilies CYP2D, CYP2E and CYP3A--part II].

Anna Wojtczak1, Jadwiga Skretkowicz.   

Abstract

Polymorphism of drugs biotransformation is clinically significant from the point of view of the effectiveness and safety of pharmacotherapy and an increased risk of some illnesses. The paper presents molecular mechanisms and clinical implication of several genetic polymorphisms of cytochrome P-450 (CYP) xenobiotics metabolizing enzymes and genetic predisposition to the occurrence of some diseases.

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Year:  2009        PMID： 19856888

Source DB:  PubMed          Journal:  Pol Merkur Lekarski        ISSN： 1426-9686


  2 in total

1.  Estimation of CYP3A4*1B single nucleotide polymorphism in patients with recurrent Major Depressive Disorder.

Authors:  Rafał Świechowski; Agnieszka Jeleń; Marek Mirowski; Monika Talarowska; Piotr Gałecki; Jacek Pietrzak; Damian Wodziński; Ewa Balcerczak
Journal:  Mol Genet Genomic Med       Date:  2019-04-25       Impact factor: 2.183

2.  CYP3A5*3 and C3435T MDR1 polymorphisms in prognostication of drug-resistant epilepsy in children and adolescents.

Authors:  Ewa Emich-Widera; Wirginia Likus; Beata Kazek; Paweł Niemiec; Anna Balcerzyk; Aleksander L Sieroń; Iwona Zak
Journal:  Biomed Res Int       Date:  2013-08-01       Impact factor: 3.411
  2 in total

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