Literature DB >> 19855859

Sleep disorders in substance abusers: how common are they?

Youssef Mahfoud1, Farid Talih, David Streem, Kumar Budur.   

Abstract

UNLABELLED: Substance abuse is a major public health problem with high morbidity and mortality. Comorbid disorders are suspected to cause a high relapse rate. Subjects with sleep disorders tend to self medicate with alcohol and tranquilizers to promote sleep or abuse stimulants to stay awake during the day. Substance abuse can, in turn, cause sleep disturbances, which can result in relapse. No studies have systematically studied the prevalence of various sleep disorders in these subjects.
METHODS: This is a cross-sectional study conducted at the Alcohol and Drug Recovery Center (ADRC) at Cleveland Clinic, Cleveland, Ohio. Subjects with active substance abuse and the ability to consent were recruited to complete a comprehensive sleep disorder questionnaire, including a general medical, psychiatric, and substance abuse history as well as validated scales (e.g., Insomnia Severity Index, Pittsburgh Sleep Quality Index (PSQI), Berlin Questionnaire for sleep apnea and restless legs).
RESULTS: Thirty patients completed the survey so far. The most commonly abused substance was alcohol (80%) followed by narcotics (40%); about 66 percent were polysubstance users. Forty-six percent of the patients reported using substance to self-medicate sleep problems. The prevalence of various sleep disorders in this population along with the prevalence in general population in parenthesis are as follows: Sleep impairment (PSQI>5) was noted in 96 percent (15%) of the subjects, and 56 percent (10-15%) had insomnia of moderate-to-severe degree. Symptoms suggestive of sleep apnea were reported in 53 percent (4-6%) of the subjects and restless leg syndrome symptoms in 33 percent (10%).
CONCLUSION: Substance abuse is on the rise and affects every aspect of society. Our study has, for the first time, systematically evaluated various sleep disorders in these subjects who seem 5 to 10 times more likely to have sleep disorders. Diagnosing and treating sleep disorders will have a huge impact in inducing remission. However, this study has significant limitations, including a small number of subjects, subjective data collected via questionnaires, and no long-term follow up, which makes it difficult to draw conclusions.

Entities:  

Keywords:  alcohol; insomnia; opiates; sleep apnea

Year:  2009        PMID: 19855859      PMCID: PMC2766287     

Source DB:  PubMed          Journal:  Psychiatry (Edgmont)        ISSN: 1550-5952


  17 in total

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Authors:  C H. Bastien; A Vallières; C M. Morin
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3.  Sleep problems and substance use in adolescence.

Authors:  E O Johnson; N Breslau
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Review 6.  Alcohol's effects on sleep in alcoholics.

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Journal:  Alcohol Res Health       Date:  2001

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Authors:  Joel E Dimsdale; Daniel Norman; Douglas DeJardin; Mark S Wallace
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Review 10.  Are sleep disturbances risk factors for anxiety, depressive and addictive disorders?

Authors:  J C Gillin
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  44 in total

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Authors:  Wei-Chen Lin; John W Winkelman
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6.  GABAA receptor positive allosteric modulators modify the abuse-related behavioral and neurochemical effects of methamphetamine in rhesus monkeys.

Authors:  Laís F Berro; Monica L Andersen; Sergio Tufik; Leonard L Howell
Journal:  Neuropharmacology       Date:  2017-05-08       Impact factor: 5.250

7.  Buprenorphine disrupts sleep and decreases adenosine concentrations in sleep-regulating brain regions of Sprague Dawley rat.

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8.  Sleep Disturbances in Australian Vietnam Veterans With and Without Posttraumatic Stress Disorder.

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9.  Insomnia severity during early abstinence is related to substance use treatment completion in adults enrolled in an intensive outpatient program.

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10.  The prevalence of sleep disturbance in alcoholics admitted for treatment: a target for chronic disease management.

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