Literature DB >> 19854692

Effectiveness of nitrous oxide and analgesic cream (lidocaine and prilocaine) for prevention of pain during intramuscular botulinum toxin injections in children.

S Brochard1, V Blajan, M Lempereur, P Le Moine, S Peudenier, J Lefranc, O Rémy-Néris.   

Abstract

AIMS: To evaluate the effectiveness of an analgesic protocol with nitrous oxide and anaesthetic cream (lidocaine and prilocaine, EMLA) for children undergoing botulinum toxin injections. PATIENTS AND METHODS: Prospective study including 51 injection sessions, 34 children with a mean age of 5.94 (range 2-15) and 209 injected muscles. Pain was evaluated with the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS), the Visual Analogue Scale (VAS) and the Face Pain Scale (FPS) for the children and with a VAS for the parents.
RESULTS: CHEOPS score for the 51 sessions was 8.50 (S.D. 3.56). Forty-nine percent of scores were above the therapeutic threshold of 9; 25% of the children evaluated the pain above the therapeutic threshold of 3; 44.74% of the parents' estimations exceeded 3. No correlation was found between age, weight, number of injected muscle and CHEOPS score.
CONCLUSION: The association of MEOPA and anaesthetic cream is only effective for 50% of children. This is much lower than treatments for other types of acute induced pain in children. Botulinum toxin injections and cerebral palsy children present certain specificities which require improvements in this analgesic protocol.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19854692     DOI: 10.1016/j.rehab.2009.09.001

Source DB:  PubMed          Journal:  Ann Phys Rehabil Med        ISSN: 1877-0657


  3 in total

Review 1.  Pain in cognitively impaired children: a focus for general pediatricians.

Authors:  M Massaro; S Pastore; A Ventura; E Barbi
Journal:  Eur J Pediatr       Date:  2012-03-20       Impact factor: 3.183

2.  Effect of a clown's presence at botulinum toxin injections in children: a randomized, prospective study.

Authors:  Lars Kjaersgaard Hansen; Maria Kibaek; Torben Martinussen; Lene Kragh; Mogens Hejl
Journal:  J Pain Res       Date:  2011-09-21       Impact factor: 3.133

Review 3.  Ultrasound Guidance for Botulinum Neurotoxin Chemodenervation Procedures.

Authors:  Katharine E Alter; Barbara I Karp
Journal:  Toxins (Basel)       Date:  2017-12-28       Impact factor: 4.546

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.