OBJECTIVES: To assess the kind and frequency of sensitisation to aeroallergens (skin prick test - SPT) of asthmatic and non-asthmatic adolescents (13-14 years old) living in the city of Caruaru, Northeast of Brazil, and to analyse their exposure to some environmental factors. METHOD: A case-control study was conducted with asthmatic (50) and non-asthmatic (150) adolescents diagnosed by the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire. All were submitted to SPT with aeroallergens (house dust mites, cat and dog epithelium, cockroaches, moulds and grass) and completed a questionnaire to evaluate their environmental exposure. RESULTS: There were no significant differences between groups regarding gender, age, number of siblings and environmental exposure. Asthmatic subjects exhibited a higher frequency of positive SPTs than non-asthmatic subjects (54.0% vs 33.3%, p=0.009) mainly due to Periplaneta americana (34.0% vs 12.7%, p=0.0007 respectively) and Canis familiaris (20.0% vs 8.7%, p=0.029). CONCLUSION: Although sensitisation to aeroallergens was high among non-asthmatic adolescents, asthma was associated with parental history of atopic disease and sensitisation to P. americana and Canis familiaris but not to D. pteronyssinus showing that local studies are mandatory for the tailoring of appropriate management of allergic diseases.
OBJECTIVES: To assess the kind and frequency of sensitisation to aeroallergens (skin prick test - SPT) of asthmatic and non-asthmatic adolescents (13-14 years old) living in the city of Caruaru, Northeast of Brazil, and to analyse their exposure to some environmental factors. METHOD: A case-control study was conducted with asthmatic (50) and non-asthmatic (150) adolescents diagnosed by the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire. All were submitted to SPT with aeroallergens (house dust mites, cat and dog epithelium, cockroaches, moulds and grass) and completed a questionnaire to evaluate their environmental exposure. RESULTS: There were no significant differences between groups regarding gender, age, number of siblings and environmental exposure. Asthmatic subjects exhibited a higher frequency of positive SPTs than non-asthmatic subjects (54.0% vs 33.3%, p=0.009) mainly due to Periplaneta americana (34.0% vs 12.7%, p=0.0007 respectively) and Canis familiaris (20.0% vs 8.7%, p=0.029). CONCLUSION: Although sensitisation to aeroallergens was high among non-asthmatic adolescents, asthma was associated with parental history of atopic disease and sensitisation to P. americana and Canis familiaris but not to D. pteronyssinus showing that local studies are mandatory for the tailoring of appropriate management of allergic diseases.
Authors: Marcela Caleffi da Costa Lima Caniatti; Ariella Andrade Marchioro; Ana Lúcia Falavigna Guilherme; Luiza Tamie Tsuneto Journal: PLoS One Date: 2014-09-19 Impact factor: 3.240
Authors: Lusmaia Damaceno Camargo Costa; Paulo Augusto Moreira Camargos; Paul L P Brand; Fabíola Souza Fiaccadori; Menira Borges de Lima Dias E Souza; Divina das Dôres de Paula Cardoso; Ítalo de Araújo Castro; Ruth Minamisava; Paulo Sérgio Sucasas da Costa Journal: BMC Pulm Med Date: 2018-07-03 Impact factor: 3.317
Authors: Eulalia Sakano; Emanuel S C Sarinho; Alvaro A Cruz; Antonio C Pastorino; Edwin Tamashiro; Fábio Kuschnir; Fábio F M Castro; Fabrizio R Romano; Gustavo F Wandalsen; Herberto J Chong-Neto; João F de Mello; Luciana R Silva; Maria Cândida Rizzo; Mônica A M Miyake; Nelson A Rosário Filho; Norma de Paula M Rubini; Olavo Mion; Paulo A Camargos; Renato Roithmann; Ricardo N Godinho; Shirley Shizue N Pignatari; Tania Sih; Wilma T Anselmo-Lima; Dirceu Solé Journal: Braz J Otorhinolaryngol Date: 2017-11-02