| Literature DB >> 19852497 |
Trine P Petersen1, Andreas Ritzén, Trond Ulven.
Abstract
A multistep continuous-flow system for synthesis of receptor ligands by assembly of three variable building blocks in a single unbroken flow is described. The sequence consists of three reactions and two scavenger steps, where a Cbz-protected diamine is reacted with an isocyanate, deprotected, and reacted further with an alkylating agent.Entities:
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Year: 2009 PMID: 19852497 DOI: 10.1021/ol902101c
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005