UNLABELLED: Recent studies claim that researchers are challenged to find out the pathogenesis of the congenital anomalies of the female reproductive tract. Their frequency is estimated to be between 0.1% and 3% of live births in humans. During the experiments a number of genes were detected to contribute to the formation and development of the female reproductive tract. This review article aims to report these genes, as they probably play a significant role in the pathology of the reproductive tract in females. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this educational activity, the participant should be better able to explain the genetic basis of Mullerian abnormalities, give examples of the complexity of the genetic basis behind a variety of mechanisms of disease, and recall the embryology of the female reproductive tract.
UNLABELLED: Recent studies claim that researchers are challenged to find out the pathogenesis of the congenital anomalies of the female reproductive tract. Their frequency is estimated to be between 0.1% and 3% of live births in humans. During the experiments a number of genes were detected to contribute to the formation and development of the female reproductive tract. This review article aims to report these genes, as they probably play a significant role in the pathology of the reproductive tract in females. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this educational activity, the participant should be better able to explain the genetic basis of Mullerian abnormalities, give examples of the complexity of the genetic basis behind a variety of mechanisms of disease, and recall the embryology of the female reproductive tract.
Authors: William W Scott; Bappaditya Ray; Kim L Rickert; Christopher J Madden; Jack M Raisanen; Dianne Mendelsohn; David Rogers; Tony A Whitworth Journal: Childs Nerv Syst Date: 2013-10-01 Impact factor: 1.475