Mohamed Hantera1. 1. Magrabi Eye & Ear Center, Dammam, Saudi Arabia. mohamedhantera30@gmail.com
Abstract
PURPOSE: To compare higher order aberrations of aspheric or wavefront-guided myopic LASIK. METHODS: This was a prospective, randomized study of a myopic LASIK cohort that was subdivided into two groups; 12 eyes were treated with theoptimized aspheric transition zone algorithm (OATz group) and 11 eyes were treated with wavefront-guided optimized path difference custom aspheric treatment (OPDCAT group). Corneal asphericity and higher order aberrations root-mean-square were compared between groups before, 1 month, and 3 months after LASIK. Student t test was used to assess differences between groups. P<.05 was considered statistically significant. RESULTS: At 3 months postoperatively, all eyes in both groups had spherical equivalent refraction of +/-0.50 diopters (D). Mean higher order aberration increased by 0.18 microm postoperatively in the OATz group (P<.05) and decreased by 0.04 microm in the OPDCAT group (P=.819). A statistically significant increase in spherical aberration was noted in the OATz group only (P<.05). Asphericity showed a statistically significant difference between the two groups postoperatively (P<.05). There was a greated tendency for increased higher order aberrations in eyes with <0.30 microm of higher order aberrations preoperatively in the OPDCAT group. The reverse tendency was observed in the OATz group. CONCLUSIONS:OPDCAT induced minimal changes in spherical aberration due to lower changes in corneal asphericity compared to the OATz group. Eyes with <0.30 microm of higher order aberrations preoperatively are likely better candidates for the OATz algorithm than OPDCAT. Copyright 2009, SLACK Incorporated.
RCT Entities:
PURPOSE: To compare higher order aberrations of aspheric or wavefront-guided myopic LASIK. METHODS: This was a prospective, randomized study of a myopic LASIK cohort that was subdivided into two groups; 12 eyes were treated with the optimized aspheric transition zone algorithm (OATz group) and 11 eyes were treated with wavefront-guided optimized path difference custom aspheric treatment (OPDCAT group). Corneal asphericity and higher order aberrations root-mean-square were compared between groups before, 1 month, and 3 months after LASIK. Student t test was used to assess differences between groups. P<.05 was considered statistically significant. RESULTS: At 3 months postoperatively, all eyes in both groups had spherical equivalent refraction of +/-0.50 diopters (D). Mean higher order aberration increased by 0.18 microm postoperatively in the OATz group (P<.05) and decreased by 0.04 microm in the OPDCAT group (P=.819). A statistically significant increase in spherical aberration was noted in the OATz group only (P<.05). Asphericity showed a statistically significant difference between the two groups postoperatively (P<.05). There was a greated tendency for increased higher order aberrations in eyes with <0.30 microm of higher order aberrations preoperatively in the OPDCAT group. The reverse tendency was observed in the OATz group. CONCLUSIONS:OPDCAT induced minimal changes in spherical aberration due to lower changes in corneal asphericity compared to the OATz group. Eyes with <0.30 microm of higher order aberrations preoperatively are likely better candidates for the OATz algorithm than OPDCAT. Copyright 2009, SLACK Incorporated.