Literature DB >> 19847446

[Effector function plasticity of T helper lymphocytes].

O Frey1, T Kamradt.   

Abstract

T helper (Th) cells are grouped into functionally different subsets (considered hitherto distinct and stable) according to their cytokine production. However, a number of recent findings show a much higher degree of Th cell plasticity and interconvertibility than previously assumed. Therefore, Th effector functions might be subject to therapeutic modulation even in late stages of immunopathological diseases.

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Year:  2009        PMID: 19847446     DOI: 10.1007/s00393-009-0559-7

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  12 in total

1.  Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.

Authors:  Edda G Schulz; Luca Mariani; Andreas Radbruch; Thomas Höfer
Journal:  Immunity       Date:  2009-04-30       Impact factor: 31.745

2.  Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells.

Authors:  Gang Wei; Lai Wei; Jinfang Zhu; Chongzhi Zang; Jane Hu-Li; Zhengju Yao; Kairong Cui; Yuka Kanno; Tae-Young Roh; Wendy T Watford; Dustin E Schones; Weiqun Peng; Hong-Wei Sun; William E Paul; John J O'Shea; Keji Zhao
Journal:  Immunity       Date:  2009-01-16       Impact factor: 31.745

Review 3.  How regulatory T cells work.

Authors:  Dario A A Vignali; Lauren W Collison; Creg J Workman
Journal:  Nat Rev Immunol       Date:  2008-07       Impact factor: 53.106

4.  Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

Authors:  Thomas Duhen; Rebekka Geiger; David Jarrossay; Antonio Lanzavecchia; Federica Sallusto
Journal:  Nat Immunol       Date:  2009-07-05       Impact factor: 25.606

5.  Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

Authors:  Marc Veldhoen; Catherine Uyttenhove; Jacques van Snick; Helena Helmby; Astrid Westendorf; Jan Buer; Bruno Martin; Christoph Wilhelm; Brigitta Stockinger
Journal:  Nat Immunol       Date:  2008-10-19       Impact factor: 25.606

6.  Late developmental plasticity in the T helper 17 lineage.

Authors:  Yun Kyung Lee; Henrietta Turner; Craig L Maynard; James R Oliver; Dongquan Chen; Charles O Elson; Casey T Weaver
Journal:  Immunity       Date:  2009-01-16       Impact factor: 31.745

Review 7.  Follicular helper T cells: lineage and location.

Authors:  Nicolas Fazilleau; Linda Mark; Louise J McHeyzer-Williams; Michael G McHeyzer-Williams
Journal:  Immunity       Date:  2009-03-20       Impact factor: 31.745

Review 8.  Th1/Th2 balance in infection.

Authors:  C Infante-Duarte; T Kamradt
Journal:  Springer Semin Immunopathol       Date:  1999

9.  Cytokine-secreting follicular T cells shape the antibody repertoire.

Authors:  R Lee Reinhardt; Hong-Erh Liang; Richard M Locksley
Journal:  Nat Immunol       Date:  2009-03-01       Impact factor: 25.606

10.  Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

Authors:  Xuyu Zhou; Samantha L Bailey-Bucktrout; Lukas T Jeker; Cristina Penaranda; Marc Martínez-Llordella; Meredith Ashby; Maki Nakayama; Wendy Rosenthal; Jeffrey A Bluestone
Journal:  Nat Immunol       Date:  2009-07-26       Impact factor: 25.606

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