AIM: This study assessed changes in depressive tendency of children with growth hormone deficiency. METHODS: The 41 children with growth hormone deficiency were assessed using the Depression Self-Rating Scale for Children. A score of 16 or more indicated a depressive tendency. The first assessment was carried out before growth hormone treatment, and the second one was carried out at 6 months or longer after the beginning of growth hormone treatment. RESULTS: The Depression Self-Rating Scale for Children improved significantly from 9.7 +/- 6.1 points before treatment to 6.9 +/- 4.6 points after treatment (P= 0.0013). A depressive tendency was observed in six patients (15%) before growth hormone treatment, and in two patients (5%) after treatment. No significant relationship was observed between the decrease in the score and the length of the treatment. A significant improvement was observed for 6 of the 18 items in the Depression Self-Rating Scale for Children. CONCLUSION: A depressive tendency was relatively common in children with growth hormone deficiency, and the Depression Self-Rating Scale for Children was decreased after growth hormone treatment. These results suggest that growth hormone treatment may have positive effects on the psychosocial aspects in children with growth hormone deficiency.
AIM: This study assessed changes in depressive tendency of children with growth hormone deficiency. METHODS: The 41 children with growth hormone deficiency were assessed using the Depression Self-Rating Scale for Children. A score of 16 or more indicated a depressive tendency. The first assessment was carried out before growth hormone treatment, and the second one was carried out at 6 months or longer after the beginning of growth hormone treatment. RESULTS: The Depression Self-Rating Scale for Children improved significantly from 9.7 +/- 6.1 points before treatment to 6.9 +/- 4.6 points after treatment (P= 0.0013). A depressive tendency was observed in six patients (15%) before growth hormone treatment, and in two patients (5%) after treatment. No significant relationship was observed between the decrease in the score and the length of the treatment. A significant improvement was observed for 6 of the 18 items in the Depression Self-Rating Scale for Children. CONCLUSION: A depressive tendency was relatively common in children with growth hormone deficiency, and the Depression Self-Rating Scale for Children was decreased after growth hormone treatment. These results suggest that growth hormone treatment may have positive effects on the psychosocial aspects in children with growth hormone deficiency.
Authors: M Mitschelen; H Yan; J A Farley; J P Warrington; S Han; C B Hereñú; A Csiszar; Z Ungvari; L C Bailey-Downs; C E Bass; W E Sonntag Journal: Neuroscience Date: 2011-04-20 Impact factor: 3.590
Authors: Beatriz Mergulhão; José Paulo Almeida; Helena Moreira; Cíntia Castro-Correia; Monika Bullinger; Maria Cristina Canavarro; Neuza Silva Journal: J Clin Psychol Med Settings Date: 2022-05-05
Authors: Meryl Brod; Michael Højby Rasmussen; Suzanne Alolga; Jane F Beck; Donald M Bushnell; Kai Wai Lee; Aristides Maniatis Journal: Pharmacoecon Open Date: 2022-10-18
Authors: Monika Bullinger; Rachel Sommer; Andreas Pleil; Nelly Mauras; Judith Ross; Ron Newfield; Lawrence Silverman; Anja Rohenkohl; Janet Fox; Julia Quitmann Journal: Health Qual Life Outcomes Date: 2015-04-02 Impact factor: 3.186
Authors: Meryl Brod; Lise Højbjerre; Suzanne Lessard Alolga; Jane F Beck; Lars Wilkinson; Michael Højby Rasmussen Journal: Patient Date: 2017-10 Impact factor: 3.883