| Literature DB >> 19845342 |
Sergio Mendez1, Erin M Fenton, Gil R Gallegos, Dimiter N Petsev, Scott S Sibbett, Howard A Stone, Yi Zhang, Gabriel P López.
Abstract
The sustained liquid flow of a typical lateral flow assay can be mimicked by two-dimensional shaped, thin porous membranes, specifically rectangular membranes appended to circular sectors. In designing these fan-shaped devices, we have been aided by analytical equations and finite-element simulations. We show both mathematically and experimentally how a continuous increase in unwetted pore volume causes a deviation from traditional imbibition, and leads to quasi-stationary flow in the rectangular element. These results are both theoretically and practically important because they indicate how medical diagnostic test strips may be fabricated without incorporating an absorbent pad.Mesh:
Substances:
Year: 2010 PMID: 19845342 DOI: 10.1021/la902470b
Source DB: PubMed Journal: Langmuir ISSN: 0743-7463 Impact factor: 3.882