| Literature DB >> 19843186 |
Chrisna Veldsman1, Marleen M Kock, Theresa Rossouw, Martin Nieuwoudt, Mark Maeurer, Anwar A Hoosen, Marthie M Ehlers.
Abstract
Tuberculosis is a life-threatening infection worldwide. Despite improvements in therapy, it results in 2 million deaths and 9 million new cases annually. This study evaluated the use of the QuantiFERON-TB GOLD enzyme-linked immunosorbent assay in a high HIV/TB burden setting in an ARV clinic at the Tshwane District Hospital, South Africa. The sensitivity and specificity of the QF assay in the clinic were 30% (9/30) and 63% (19/30), respectively, when compared with the gold standard culture results. Analysis also suggested that the sensitivity of the QuantiFERON assay is determined by a limiting patient CD4 value between 150 and 200.Entities:
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Year: 2009 PMID： 19843186 DOI： 10.1111/j.1574-695X.2009.00610.x
Source DB: PubMed Journal: FEMS Immunol Med Microbiol ISSN： 0928-8244