Literature DB >> 19841915

Perception of risk regarding the use of medications and other exposures during pregnancy.

Hedvig Nordeng1, Eivind Ystrøm, Adrienne Einarson.   

Abstract

BACKGROUND: Perception of risk may impact a woman's decision to take a needed drug during pregnancy. There is a paucity of research on this topic in the literature.
OBJECTIVES: (1) To evaluate the perception of risk of 17 commonly used drugs and other substances by pregnant women. (2) To investigate which sources of information regarding exposures during pregnancy were most commonly used by women.
METHODS: A questionnaire was developed through the University of Oslo's website for Internet surveys and posted on four Web pages used by pregnant women and mothers, from mid-September 2008 through October 2008. The inclusion criteria included women who were (1) pregnant or 2) a mother of a child less than 5 years old.
RESULTS: A total of 1,793 eligible women completed the questionnaire. Most women overestimated the teratogenic risk associated with all the drugs during pregnancy. Characteristics of the women that were associated with a high perception of risk were primiparity, higher age, higher education, and choosing not to use a drug during pregnancy. More than 80% of the women had used drugs during pregnancy, mostly paracetamol, penicillins and reflux medications. The physician, the product information leaflet and the pharmacist were the three most frequently used sources of information.
CONCLUSION: Women overestimate the risk of drug use and other exposures during pregnancy. Therefore, it is important for health care providers to use evidence-based information, to reduce unnecessary anxiety, and to ensure safe and appropriate treatment during pregnancy.

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Mesh:

Year:  2009        PMID: 19841915     DOI: 10.1007/s00228-009-0744-2

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  17 in total

1.  Exposure to ionizing radiation during pregnancy: perception of teratogenic risk and outcome.

Authors:  Y Bentur; N Horlatsch; G Koren
Journal:  Teratology       Date:  1991-02

2.  Disparities in rates of unintended pregnancy in the United States, 1994 and 2001.

Authors:  Lawrence B Finer; Stanley K Henshaw
Journal:  Perspect Sex Reprod Health       Date:  2006-06

Review 3.  The effectiveness of Teratology Information Services (TIS).

Authors:  Rebecca L Hancock; Gideon Koren; Adrienne Einarson; Wendy J Ungar
Journal:  Reprod Toxicol       Date:  2006-11-18       Impact factor: 3.143

4.  Herbal products: behaviors and beliefs among Italian women.

Authors:  Silvana Zaffani; Laura Cuzzolin; Giuseppina Benoni
Journal:  Pharmacoepidemiol Drug Saf       Date:  2006-05       Impact factor: 2.890

5.  Diagnostic radiation in pregnancy: perception versus true risks.

Authors:  Raanan Cohen-Kerem; Irena Nulman; Maria Abramow-Newerly; Damien Medina; Ronnen Maze; Robert L Brent; Gideon Koren
Journal:  J Obstet Gynaecol Can       Date:  2006-01

6.  Advice on drug safety in pregnancy: are there differences between commonly used sources of information?

Authors:  Sofia K Frost Widnes; Jan Schjøtt
Journal:  Drug Saf       Date:  2008       Impact factor: 5.606

7.  Use of herbal preparations during pregnancy: focus group discussion among expectant mothers attending a hospital antenatal clinic in Norwich, UK.

Authors:  Lone Holst; David Wright; Hedvig Nordeng; Svein Haavik
Journal:  Complement Ther Clin Pract       Date:  2009-05-22       Impact factor: 2.446

8.  Use of antidepressants by pregnant women: evaluation of perception of risk, efficacy of evidence based counseling and determinants of decision making.

Authors:  L Bonari; G Koren; T R Einarson; J D Jasper; A Taddio; A Einarson
Journal:  Arch Womens Ment Health       Date:  2005-06-17       Impact factor: 3.633

9.  Questions about drugs: how do pregnant women solve them?

Authors:  A M van Trigt; C M Waardenburg; F M Haaijer-Ruskamp; L T de Jong-van den Berg
Journal:  Pharm World Sci       Date:  1994-12-02

10.  A descriptive study of the use of the Internet by women seeking pregnancy-related information.

Authors:  Margareta Larsson
Journal:  Midwifery       Date:  2007-04-03       Impact factor: 2.372

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  63 in total

1.  Birth defects, causal attributions, and ethnicity in the national birth defects prevention study.

Authors:  Amy P Case; Marjorie Royle; Angela E Scheuerle; Suzan L Carmichael; Karen Moffitt; Tunu Ramadhani
Journal:  J Genet Couns       Date:  2014-03-29       Impact factor: 2.537

2.  Drugs and Birth Defects: a knowledge database providing risk assessments based on national health registers.

Authors:  Ulrika Nörby; Karin Källén; Birgit Eiermann; Seher Korkmaz; Birger Winbladh; Lars L Gustafsson
Journal:  Eur J Clin Pharmacol       Date:  2012-09-26       Impact factor: 2.953

3.  Pregnancy and lactation advice: How does Australian Product Information compare with established information resources?

Authors:  Emma Brown; Elizabeth Hotham; Neil Hotham
Journal:  Obstet Med       Date:  2016-04-28

4.  The Perinatal Treatment Conundrum.

Authors:  Sophie Grigoriadis; Miki Peer
Journal:  Can J Psychiatry       Date:  2017-08       Impact factor: 4.356

5.  Counselling pregnant women at the crossroads of Europe and Asia: effect of Teratology Information Service in Turkey.

Authors:  Yusuf Cem Kaplan; Barış Karadaş; Gözde Küçüksolak; Bartu Ediz; Ömer Demir; Kaan Sozmen; Hedvig Nordeng
Journal:  Int J Clin Pharm       Date:  2017-06-19

Review 6.  Antidepressant use in pregnancy: a critical review focused on risks and controversies.

Authors:  N Byatt; K M Deligiannidis; M P Freeman
Journal:  Acta Psychiatr Scand       Date:  2012-12-14       Impact factor: 6.392

Review 7.  Frequency and type of medications and vaccines used during pregnancy.

Authors:  Diego F Wyszynski; Kristine E Shields
Journal:  Obstet Med       Date:  2015-09-30

8.  Use of antimigraine medications and information needs during pregnancy and breastfeeding: a cross-sectional study among 401 Norwegian women.

Authors:  Siri Amundsen; Torunn G Øvrebø; Netta Marie S Amble; Anne Christine Poole; Hedvig Nordeng
Journal:  Eur J Clin Pharmacol       Date:  2016-09-13       Impact factor: 2.953

9.  Teratogenic risk perception and confidence in use of medicines in pairs of pregnant women and general practitioners based on patient information leaflets.

Authors:  Sofia Frost Widnes; Jan Schjøtt; Geir Egil Eide; Anne Gerd Granas
Journal:  Drug Saf       Date:  2013-06       Impact factor: 5.606

Review 10.  Use of Antidepressants During Pregnancy?: What to Consider when Weighing Treatment with Antidepressants Against Untreated Depression.

Authors:  Maria Muzik; Susan E Hamilton
Journal:  Matern Child Health J       Date:  2016-11
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