Literature DB >> 19841814

Gd(DO3A-N-alpha-aminopropionate): a versatile and easily available synthon with optimized water exchange for the synthesis of high relaxivity, targeted MRI contrast agents.

Miguel F Ferreira1, André F Martins, José A Martins, Paula M Ferreira, Eva Tóth, Carlos F G C Geraldes.   

Abstract

We report the synthesis of a novel, versatile and easily accessible metal chelator, DO3A-N-alpha-aminopropionate, and the relaxometric characterization of its Gd(3+) complex, revealing great potential for the development of high relaxivity targeted contrast agents for magnetic resonance imaging.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19841814     DOI： 10.1039/b912201j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

Review 1.  Basic MR relaxation mechanisms and contrast agent design.

Authors:  Luis M De León-Rodríguez; André F Martins; Marco C Pinho; Neil M Rofsky; A Dean Sherry
Journal:  J Magn Reson Imaging       Date:  2015-05-14       Impact factor: 4.813

2.  Reporter protein-targeted probes for magnetic resonance imaging.

Authors:  Renee C Strauch; Daniel J Mastarone; Preeti A Sukerkar; Ying Song; Jonathan J Ipsaro; Thomas J Meade
Journal:  J Am Chem Soc       Date:  2011-09-26       Impact factor: 15.419

3.  Unexpected Changes in the Population of Coordination Isomers for the Lanthanide Ion Complexes of DOTMA-Tetraglycinate.

Authors:  Cemile Kumas; W Shirangi Fernando; Piyu Zhao; Martín Regueiro-Figueroa; Garry E Kiefer; André F Martins; Carlos Platas-Iglesias; A Dean Sherry
Journal:  Inorg Chem       Date:  2016-09-07       Impact factor: 5.165

4.  A novel zinc bis(thiosemicarbazone) complex for live cell imaging.

Authors:  Disha Dayal; Duraippandi Palanimuthu; Sridevi Vijay Shinde; Kumaravel Somasundaram; Ashoka G Samuelson
Journal:  J Biol Inorg Chem       Date:  2011-03-08       Impact factor: 3.358

5.  Gd(DOTAla): a single amino acid Gd-complex as a modular tool for high relaxivity MR contrast agent development.

Authors:  Eszter Boros; Miloslav Polasek; Zhaoda Zhang; Peter Caravan
Journal:  J Am Chem Soc       Date:  2012-11-16       Impact factor: 15.419

6.  Gd(DOTAlaP): exploring the boundaries of fast water exchange in gadolinium-based magnetic resonance imaging contrast agents.

Authors:  Eszter Boros; Shima Karimi; Nathaniel Kenton; Lothar Helm; Peter Caravan
Journal:  Inorg Chem       Date:  2014-06-12       Impact factor: 5.165
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.