Literature DB >> 19841144

In vitro activity of thimerosal against ocular pathogenic fungi.

Yan Xu1, Guangren Pang, Dongqing Zhao, Chuanwen Gao, Lutan Zhou, Shengtao Sun, Bingliang Wang.   

Abstract

The in vitro activity of thimerosal versus those of amphotericin B and natamycin was assessed against 244 ocular fungal isolates. The activity of thimerosal against Fusarium spp., Aspergillus spp., and Alternaria alternata was 256 times, 512 times, and 128 times, respectively, greater than that of natamycin and 64 times, 32 times, and 32 times, respectively, greater than that of amphotericin B. Thimerosal's antifungal activity was significantly superior to those of amphotericin B and natamycin against ocular pathogenic fungi in vitro.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19841144      PMCID： PMC2798525          DOI： 10.1128/AAC.00714-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  24 in total

1.  MERCURIAL PRESERVATIVES IN EYE-DROPS, OBSERVATIONS ON PATIENTS USING MIOTICS CONTAINING THIOMERSAL.

Authors:  J D ABRAMS; T G DAVIES; M KLEIN
Journal:  Br J Ophthalmol       Date:  1965-03       Impact factor: 4.638

2.  Clinical and microbial spectrum of fungal keratitis in Singapore: a 5-year retrospective study.

Authors:  T Y Wong; K S Fong; D T Tan
Journal:  Int Ophthalmol       Date:  1997       Impact factor: 2.031

3.  Cytotoxicity of ophthalmic preservatives.

Authors:  A R Gasset; Y Ishii; H E Kaufman; T Miller
Journal:  Am J Ophthalmol       Date:  1974-07       Impact factor: 5.258

4.  Corneal penetration of topical amphotericin B and natamycin.

Authors:  D M O'Day; W S Head; R D Robinson; J A Clanton
Journal:  Curr Eye Res       Date:  1986-11       Impact factor: 2.424

5.  [Laboratory study of the mycotic infectious eye diseases and factors associated with keratitis].

Authors:  Ana Luisa Höfling-Lima; Adriana Forseto; João Paulo Duprat; Alfredo Andrade; Luciene Barbosa de Souza; Patrício Godoy; Denise de Freitas
Journal:  Arq Bras Oftalmol       Date:  2005-03-30       Impact factor: 0.872

6.  Fungal spectrum identified by a new slide culture and in vitro drug susceptibility using Etest in fungal keratitis.

Authors:  Wen-Ya Qiu; Yu-Feng Yao; Ye-Fei Zhu; Yong-Ming Zhang; Ping Zhou; Yi-Qi Jin; Bei Zhang
Journal:  Curr Eye Res       Date:  2005-12       Impact factor: 2.424

7.  Spectrum of fungal keratitis in North India.

Authors:  Anuradha Chowdhary; Kirti Singh
Journal:  Cornea       Date:  2005-01       Impact factor: 2.651

8.  Fungal keratitis in Saudi Arabia.

Authors:  S H Khairallah; K A Byrne; K F Tabbara
Journal:  Doc Ophthalmol       Date:  1992       Impact factor: 2.379

9.  Laboratory diagnosis in ulcerative keratitis.

Authors:  B Khanal; M Deb; A Panda; Harinder Singh Sethi
Journal:  Ophthalmic Res       Date:  2005-03-04       Impact factor: 2.892

10.  [Otomycosis and topical application of thimerosal: study of 152 cases].

Authors:  J Tisner; J Millán; P Rivas; I Adiego; A Castellote; H Valles
Journal:  Acta Otorrinolaringol Esp       Date:  1995 Mar-Apr
View more
  4 in total

1.  Natamycin and Azithromycin Are Synergistic In Vitro against Ocular Pathogenic Aspergillus flavus Species Complex and Fusarium solani Species Complex Isolates.

Authors:  Haoyi Guo; Lutan Zhou; Yi He; Chuanwen Gao; Lei Han; Yan Xu
Journal:  Antimicrob Agents Chemother       Date:  2018-06-26       Impact factor: 5.191

2.  Acute exposure to thimerosal induces antiproliferative properties, apoptosis, and autophagy activation in human Chang conjunctival cells.

Authors:  Huina Zhang; Han Wu; Changjun Wang; Jiajun Xie; Jinjing He; Jun Yang; Juan Ye
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-01-03       Impact factor: 3.117

3.  Rifampin Enhances the Activity of Amphotericin B against Fusarium solani Species Complex and Aspergillus flavus Species Complex Isolates from Keratitis Patients.

Authors:  Yi He; Lutan Zhou; Chuanwen Gao; Lei Han; Yan Xu
Journal:  Antimicrob Agents Chemother       Date:  2017-03-24       Impact factor: 5.191

4.  Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors.

Authors:  Sewar Alkhashrom; Jintawee Kicuntod; Sigrun Häge; Johannes Schweininger; Yves A Muller; Peter Lischka; Manfred Marschall; Jutta Eichler
Journal:  Viruses       Date:  2021-03-12       Impact factor: 5.048
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.