Literature DB >> 1983983

Studies of Cs retention in the human body related to body parameters and Prussian blue administration.

J L Lipsztein1, L Bertelli, C A Oliveira, B M Dantas.   

Abstract

Using the in-vivo monitoring data from the individuals that suffered internal contamination in the Goiânia accident, a preliminary study on the elimination of Cs from their body was conducted. It was concluded that elimination follows a first-order linear kinetic pattern, both with and without Prussian Blue treatment. Cesium half-lives for both sexes were shown to be influenced mainly by the weight of each individual. In general, Prussian Blue seems to reduce the half-life by 32%. At the time our study was conducted, patients who were under treatment with the drug were receiving 3 g d-1, 6 g d-1, or 10 g d-1 of the medication. Our results suggest that there is an optimum dosage for a certain weight range to achieve this reduction in half-life, but one would need more data to statistically prove this assumption.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1983983     DOI: 10.1097/00004032-199101000-00008

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  1 in total

1.  In vitro and in vivo evaluation of a novel ferrocyanide functionalized nanopourous silica decorporation agent for cesium in rats.

Authors:  Charles Timchalk; Jeffrey A Creim; Vichaya Sukwarotwat; Robert Wiacek; R Shane Addleman; Glen E Fryxell; Wassana Yantasee
Journal:  Health Phys       Date:  2010-09       Impact factor: 1.316

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.