Esophageal gastrointestinal stromal tumor with pulmonary and bone metastases.

Gastrointestinal stromal tumors (GISTs) are rare neoplasms of the gastrointestinal tract. One to three percent of GISTs occur in the esophagus. GISTs have a great potential for diffuse intra- abdominal spread and liver metastasis, which are the two most common modes of dissemination. Metastases to other sites, especially the bones and lung, are relatively rare. Never has an esophageal GIST been documented to present with pulmonary and bone metastases. We present an unusual case of an esophageal GIST with pulmonary and bone lesions. We include a review of the literature.