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Literature DB >> 19838234

Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography.

Vivek J Srinivasan¹, Sava Sakadzić, Iwona Gorczynska, Svetlana Ruvinskaya, Weicheng Wu, James G Fujimoto, David A Boas.

Abstract

We describe depth-resolved microscopy of cortical hemodynamics with high-speed spectral/Fourier domain optical coherence tomography (OCT). Stimulus-evoked changes in blood vessel diameter, flow, and total hemoglobin were measured in the rat somatosensory cortex. The results show OCT measurements of hemodynamic changes during functional activation and represent an important step toward understanding functional hyperemia at the microscopic level.

Entities: Chemical Disease Species

Mesh：

Year: 2009 PMID： 19838234 PMCID： PMC2778254 DOI： 10.1364/OL.34.003086

Source DB: PubMed Journal: Opt Lett ISSN： 0146-9592 Impact factor: 3.776

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