Literature DB >> 19838082

PI3K signaling in lymphocyte migration.

Aurore Saudemont1, Francesco Colucci.   

Abstract

Lymphocyte migration is crucial for immunological surveillance. A better understanding of the mechanisms that regulate lymphocyte migration will help appreciate how lymphocytes deliver specific functions to appropriate anatomical sites. Phosphoinositide-3 kinases (PI3Ks) are lipid kinases that regulate numerous cellular responses, including cell motility and chemotaxis. Here we discuss how PI3K isoforms differentially regulate lymphocyte migration and trafficking, with an emphasis on natural killer cells.

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Year:  2009        PMID： 19838082     DOI： 10.4161/cc.8.20.9692

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  10 in total

1.  PI3K/Akt pathway mediates high glucose-induced lipogenesis and extracellular matrix accumulation in HKC cells through regulation of SREBP-1 and TGF-β1.

Authors:  Jun Hao; Shuxia Liu; Song Zhao; Qingjuan Liu; Xin Lv; Huan Chen; Yunyi Niu; Huijun Duan
Journal:  Histochem Cell Biol       Date:  2011-01-15       Impact factor: 4.304

Review 2.  Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.

Authors:  Linda S Steelman; William H Chappell; Stephen L Abrams; Ruth C Kempf; Jacquelyn Long; Piotr Laidler; Sanja Mijatovic; Danijela Maksimovic-Ivanic; Franca Stivala; Maria C Mazzarino; Marco Donia; Paolo Fagone; Graziella Malaponte; Ferdinando Nicoletti; Massimo Libra; Michele Milella; Agostino Tafuri; Antonio Bonati; Jörg Bäsecke; Lucio Cocco; Camilla Evangelisti; Alberto M Martelli; Giuseppe Montalto; Melchiorre Cervello; James A McCubrey
Journal:  Aging (Albany NY)       Date:  2011-03       Impact factor: 5.682

Review 3.  PI3K functions in cancer progression, anticancer immunity and immune evasion by tumors.

Authors:  Francesco Dituri; Antonio Mazzocca; Gianluigi Giannelli; Salvatore Antonaci
Journal:  Clin Dev Immunol       Date:  2011-10-20

4.  Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells.

Authors:  Jackson R Taylor; Brian D Lehmann; William H Chappell; Stephen L Abrams; Linda S Steelman; James A McCubrey
Journal:  Oncotarget       Date:  2011-08

5.  The Regulation of Lipid Deposition by Insulin in Goose Liver Cells Is Mediated by the PI3K-AKT-mTOR Signaling Pathway.

Authors:  Chunchun Han; Shouhai Wei; Fang He; Dandan Liu; Huofu Wan; Hehe Liu; Liang Li; Hongyong Xu; Xiaohui Du; Feng Xu
Journal:  PLoS One       Date:  2015-05-06       Impact factor: 3.240

6.  TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways.

Authors:  Xianyi Meng; Chenghong Zhang; Yu Guo; Ying Han; Chunyang Wang; Haiying Chu; Li Kong; Haiying Ma
Journal:  Oxid Med Cell Longev       Date:  2020-04-13       Impact factor: 6.543

Review 7.  Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors?

Authors:  Ebru Aydin; Sebastian Faehling; Mariam Saleh; Laura Llaó Cid; Martina Seiffert; Philipp M Roessner
Journal:  Front Immunol       Date:  2021-01-20       Impact factor: 7.561

8.  6,7,4'-Trihydroxyflavanone Mitigates Methamphetamine-Induced Neurotoxicity in SH-SY5y Cells via Nrf2/heme Oxyganase-1 and PI3K/Akt/mTOR Signaling Pathways.

Authors:  Hyun-Su Lee; Gil-Saeng Jeong
Journal:  Molecules       Date:  2021-04-22       Impact factor: 4.411

9.  Superoxide mediates direct current electric field-induced directional migration of glioma cells through the activation of AKT and ERK.

Authors:  Fei Li; Tunan Chen; Shengli Hu; Jiangkai Lin; Rong Hu; Hua Feng
Journal:  PLoS One       Date:  2013-04-16       Impact factor: 3.240

10.  Role of inositol phospholipid signaling in natural killer cell biology.

Authors:  Matthew Gumbleton; William G Kerr
Journal:  Front Immunol       Date:  2013-03-06       Impact factor: 7.561
  10 in total

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