| Literature DB >> 19837751 |
Michael J Welch1, Craig J Hawker, Karen L Wooley.
Abstract
Nanoparticles have an advantage for molecular imaging in that many functionalities can be added to the surface and interior of the particle. This brief review focuses on the design of nanomaterials that take advantage of PET. An evolutionary approach is presented, leading to the optimization of the nanoparticle composition and structure to achieve controlled in vivo circulation and tissue-selective targeting. Organic and inorganic nanostructures are included. Nanoprobes for PET of angiogenesis and cancer are highlighted.Entities:
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Year: 2009 PMID: 19837751 DOI: 10.2967/jnumed.109.061846
Source DB: PubMed Journal: J Nucl Med ISSN: 0161-5505 Impact factor: 10.057