| Literature DB >> 19837144 |
N P Rybalchenko1, V A Prykhodko, S S Nagorna, N N Volynets, A N Ostapchuk, V V Klochko, T V Rybalchenko, L V Avdeeva.
Abstract
In vitro antifungal activity of phenylheptatriyne from Bidens cernua L. (Asteraceae) was studied using broth macrodilution method against 125 strains of yeasts including 104 clinical and other isolates of Candida spp. (C. albicans, C. krusei, C. tropicalis, C. guilliermondii, C. parapsilosis, C. glabrata, C. inconspicua), 16 strains of basidiomycetous yeasts (Cryptococcus neoformans, C. albidus, Trichosporon cutaneum, Rhodotorula glutinis) and five standard reference strains of Candida species. Phenylheptatriyne has shown significant activity against investigated strains, and the Minimal Inhibitory Concentrations for Candida spp. were determined as 12.5-50 microg/ml and for basidiomycetous yeasts as 12.5-100 microg/ml. Copyright 2009 Elsevier B.V. All rights reserved.Entities:
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Year: 2009 PMID： 19837144 DOI： 10.1016/j.fitote.2009.10.007
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882