Literature DB >> 19834404

Stereotactic radiosurgery for cavernous sinus or orbital hemangiomas.

Aftab A Khan1, Ajay Niranjan, Hideyuki Kano, Douglas Kondziolka, John C Flickinger, L Dade Lunsford.   

Abstract

OBJECTIVE: Hemangiomas are rare but highly vascular tumors that may develop in the cavernous sinus or orbit. These tumors pose diagnostic as well as therapeutic challenges to neurosurgeons during attempted removal. We analyzed our increasing experience using stereotactic radiosurgery (SRS).
METHODS: Eight symptomatic patients with hemangiomas underwent SRS between 1988 and 2007. The presenting symptoms included headache, orbital pain, diplopia, ptosis, proptosis and impaired visual acuity. The hemangiomas were located in either the cavernous sinus (7 patients) or the orbit (1 patient). Four patients underwent SRS as primary treatment modality based on clinical and imaging criteria. Four patients had previous microsurgical partial excision or biopsy. The median target volume was 6.8 mL (range, 2.5-18 mL). The median prescription dose delivered to the margin was 14.5 Gy (range, 12.5-19 Gy). The dose to the optic nerve in all patients was less than 9 Gy (range, 4.5-9 Gy).
RESULTS: The median follow-up period after SRS was 80 months (range, 40-127 months). Six patients had symptomatic improvement; 2 patients reported persistent diplopia. Follow-up imaging revealed tumor regression in 7 patients and no change in tumor volume in 1 patient. All the patients improved after SRS.
CONCLUSION: Our extended experience confirms that SRS is an effective management strategy for symptomatic intracavernous and intraorbital hemangiomas. Our study is the first long-term report on the safety and efficacy of SRS.

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Year:  2009        PMID: 19834404     DOI: 10.1227/01.NEU.0000356987.98197.71

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  7 in total

Review 1.  The role of stereotactic radiosurgery in cavernous sinus hemangiomas: a systematic review and meta-analysis.

Authors:  Xin Wang; Guanghai Mei; Xiaoxia Liu; Jiazhong Dai; Li Pan; Enmin Wang
Journal:  J Neurooncol       Date:  2011-11-16       Impact factor: 4.130

2.  Stereotactic gamma knife radiosurgery for orbital cavernous hemangioma: clinical outcome and visual function protection.

Authors:  Hsien-Chung Chen; Chaur-Jong Hu; David Hung-Chi Pan
Journal:  J Neurooncol       Date:  2021-01-24       Impact factor: 4.130

3.  Stereotactic radiosurgery for cavernous sinus hemangiomas.

Authors:  Sang Woo Song; Dong Gyu Kim; Hyun-Tai Chung; Sun Ha Paek; Jung Ho Han; Yong Hwy Kim; Jin Wook Kim; Young-Hoon Kim; Hee-Won Jung
Journal:  J Neurooncol       Date:  2014-03-02       Impact factor: 4.130

4.  Stereotactic radiosurgery for orbital cavernous venous malformation: a single center's experience for 15 years.

Authors:  Won Jae Lee; Kyung-Rae Cho; Jung-Won Choi; Doo-Sik Kong; Ho Jun Seol; Do-Hyun Nam; Yoon-Duck Kim; Kyung In Woo; Jung-Il Lee
Journal:  Acta Neurochir (Wien)       Date:  2020-09-15       Impact factor: 2.216

Review 5.  Safety and efficacy of single-fraction gamma knife radiosurgery for benign confined cavernous sinus tumors: our experience and literature review.

Authors:  Manjul Tripathi; Aman Batish; Narendra Kumar; Chirag Kamal Ahuja; Arun S Oinam; Rupinder Kaur; Rajasekhar Narayanan; Jenil Gurnaani; Amanjot Kaur
Journal:  Neurosurg Rev       Date:  2018-04-09       Impact factor: 3.042

6.  Progressive tentorial cavernous malformation.

Authors:  Takuya Furuta; Mitsutoshi Nakada; Takuya Watanabe; Yutaka Hayashi; Jun-Ichiro Hamada
Journal:  Surg Neurol Int       Date:  2012-02-15

7.  Fractionated Radiation Therapy for Large and Giant Cavernous Sinus Hemangioma: A Retrospective Study.

Authors:  Zengfeng Xin; Yihan Yao; Guodi Chen; Liancong Wang; Meibao Shu; Qinghua Lv; Haifeng Yu; Ting Zhang
Journal:  Front Neurol       Date:  2020-05-13       Impact factor: 4.003

  7 in total

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