OBJECTIVE: Choroid plexus carcinoma (CPCa) is an uncommon tumor rarely occurring in patients older than 2 years of age. The case reported herein represents the first documented example of a primary supratentorial, extraventricular CPCa in an adult. The scant literature regarding this topic is reviewed. CLINICAL PRESENTATION: A 68-year-old woman presented with transient expressive aphasia. Magnetic resonance imaging demonstrated an avidly enhancing, left temporal, extra-axial mass with associated parenchymal cysts. INTERVENTION: The tumor was gross-totally removed via a frontotemporal craniotomy. A diagnosis of CPCa was made on histological, immunohistochemical, and ultrastructural grounds. Postoperatively, the patient was treated by local radiotherapy and temozolomide. A magnetic resonance imaging scan 44 months after surgery showed no evidence of residual or recurrent tumor. CONCLUSION: CPCa infrequently affects adults. Only rarely does it present as a supratentorial, extraventricular mass. Resection is the mainstay of therapy. Adjuvant radiation and chemotherapy are rational treatment options.
OBJECTIVE:Choroid plexus carcinoma (CPCa) is an uncommon tumor rarely occurring in patients older than 2 years of age. The case reported herein represents the first documented example of a primary supratentorial, extraventricular CPCa in an adult. The scant literature regarding this topic is reviewed. CLINICAL PRESENTATION: A 68-year-old woman presented with transient expressive aphasia. Magnetic resonance imaging demonstrated an avidly enhancing, left temporal, extra-axial mass with associated parenchymal cysts. INTERVENTION: The tumor was gross-totally removed via a frontotemporal craniotomy. A diagnosis of CPCa was made on histological, immunohistochemical, and ultrastructural grounds. Postoperatively, the patient was treated by local radiotherapy and temozolomide. A magnetic resonance imaging scan 44 months after surgery showed no evidence of residual or recurrent tumor. CONCLUSION: CPCa infrequently affects adults. Only rarely does it present as a supratentorial, extraventricular mass. Resection is the mainstay of therapy. Adjuvant radiation and chemotherapy are rational treatment options.
Authors: Martin M Mortazavi; Christoph J Griessenauer; Nimer Adeeb; Aman Deep; Reza Bavarsad Shahripour; Reza Bavarsad Shahripour; Marios Loukas; Richard Isaiah Tubbs; R Shane Tubbs Journal: Childs Nerv Syst Date: 2013-11-28 Impact factor: 1.475
Authors: Roy W R Dudley; Michelle R Torok; Danielle Gallegos; Arthur K Liu; Michael H Handler; Todd C Hankinson Journal: J Neurooncol Date: 2014-10-09 Impact factor: 4.130
Authors: Matthew Z Sun; Michael C Oh; Michael E Ivan; Gurvinder Kaur; Michael Safaee; Joseph M Kim; Joanna J Phillips; Kurtis I Auguste; Andrew T Parsa Journal: Neurosurg Rev Date: 2013-09-26 Impact factor: 3.042