Literature DB >> 19833053

Gene-directed enzyme prodrug therapy for cancer: a glimpse into the future?

Gerald W Both1.   

Abstract

Gene-directed enzyme prodrug therapy offers a new approach to treating some cancers. Clinical trials have been completed for brain and prostate cancers and the first product for post-surgical treatment of some brain tumors is awaiting marketing approval. Recent innovations provide a glimpse into the possible future evolution of a new gene medicine.

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Year:  2009        PMID： 19833053

Source DB:  PubMed          Journal:  Discov Med        ISSN： 1539-6509            Impact factor:   2.970


  4 in total

Review 1.  Adenoviral vectors for prodrug activation-based gene therapy for cancer.

Authors:  Joshua C Doloff; David J Waxman
Journal:  Anticancer Agents Med Chem       Date:  2014-01       Impact factor: 2.505

2.  Combined antitumor activity of the nitroreductase/CB1954 suicide gene system and γ-rays in HeLa cells in vitro.

Authors:  Geling Teng; Yuanrong Ju; Yepeng Yang; Hu Hua; Jingyu Chi; Xiuan Mu
Journal:  Mol Med Rep       Date:  2016-11-01       Impact factor: 2.952

3.  Novel therapeutic approaches for various cancer types using a modified sleeping beauty-based gene delivery system.

Authors:  In-Sun Hong; Hwa-Yong Lee; Hyun-Pyo Kim
Journal:  PLoS One       Date:  2014-01-21       Impact factor: 3.240

4.  Towards feedback-controlled nanomedicines for smart, adaptive delivery.

Authors:  Stephen J Jones; Annette F Taylor; Paul A Beales
Journal:  Exp Biol Med (Maywood)       Date:  2018-09-11
  4 in total

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