Literature DB >> 1983156

Oxidative deamination of aliphatic amines by rat aorta semicarbazide-sensitive amine oxidase.

P H Yu1.   

Abstract

Rat aorta semicarbazide-sensitive amine oxidase (SSAO) exhibits very high affinity in the deamination of an homologous series of aliphatic amines of 1 to 18 straight chain carbon atoms. The Km value decreases substantially as the chain length of these amines increases. The Vmax values are higher for the short chain amines. Diamines are poor substrates for SSAO or are not acted upon by the enzyme. The substrate preference for SSAO differs from that for monoamine oxidase.

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Year:  1990        PMID： 1983156     DOI： 10.1111/j.2042-7158.1990.tb07048.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  12 in total

1.  Formation of formaldehyde from adrenaline in vivo; a potential risk factor for stress-related angiopathy.

Authors:  P H Yu; C T Lai; D M Zuo
Journal:  Neurochem Res       Date:  1997-05       Impact factor: 3.996

2.  Platelet MAO-B activity and serotonin content in patients with dementia: effect of age, medication, and disease.

Authors:  Z Mészáros; D Borcsiczky; M Máté; J Tarcali; T Szombathy; K Tekes; K Magyar
Journal:  Neurochem Res       Date:  1998-06       Impact factor: 3.996

3.  Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation.

Authors:  Peter H Yu; Li-Xin Lu; Hui Fan; Mychaylo Kazachkov; Zhong-Jian Jiang; Sirpa Jalkanen; Craig Stolen
Journal:  Am J Pathol       Date:  2006-03       Impact factor: 4.307

4.  Aminoguanidine inhibits semicarbazide-sensitive amine oxidase activity: implications for advanced glycation and diabetic complications.

Authors:  P H Yu; D M Zuo
Journal:  Diabetologia       Date:  1997-11       Impact factor: 10.122

5.  Determination of human serum semicarbazide-sensitive amine oxidase activity: a possible clinical marker of atherosclerosis.

Authors:  Z Mészáros; I Karádi; A Csányi; T Szombathy; L Romics; K Magyar
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1999 Oct-Dec       Impact factor: 2.441

6.  Semicarbazide-sensitive amine oxidase activation promotes adipose conversion of 3T3-L1 cells.

Authors:  N Mercier; M Moldes; K El Hadri; B Fève
Journal:  Biochem J       Date:  2001-09-01       Impact factor: 3.857

Review 7.  Semicarbazide-sensitive amine oxidase (SSAO) in the brain.

Authors:  Toshio Obata
Journal:  Neurochem Res       Date:  2002-04       Impact factor: 3.996

8.  Formaldehyde promotes and inhibits the proliferation of cultured tumour and endothelial cells.

Authors:  E Tyihák; J Bocsi; F Timár; G Rácz; B Szende
Journal:  Cell Prolif       Date:  2001-06       Impact factor: 6.831

9.  Increase of formation of methylamine and formaldehyde in vivo after administration of nicotine and the potential cytotoxicity.

Authors:  P H Yu
Journal:  Neurochem Res       Date:  1998-09       Impact factor: 3.996

10.  Comparison of phenelzine and geometric isomers of its active metabolite, β-phenylethylidenehydrazine, on rat brain levels of amino acids, biogenic amine neurotransmitters and methylamine.

Authors:  Dmitriy Matveychuk; Emerson Nunes; Nasir Ullah; Carlos A Velázquez-Martinez; Erin M MacKenzie; Glen B Baker
Journal:  J Neural Transm (Vienna)       Date:  2013-02-08       Impact factor: 3.575
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