Literature DB >> 19830414

Temporary risk identification in urolithiasis.

Y M Fazil Marickar1, Abiya Salim.   

Abstract

We have been using a risk index calculation for urolithiasis, which included most of the identifiable factors promoting calculogenesis. However, it was observed that the frequency of a patient getting stone problem was not uniform in spite of similarity of the risk index in the permanent setting. Also, many of the risk indices could be changed by dietary or lifestyle modifications. The objective of this paper was to calculate the temporary risk index of a patient at the time of each visit and correlate with stone activity during such periods, so that appropriate advice could be given on drugs, diet and lifestyle changes. The temporary risk index score was based on four symptoms, namely pain (0, nil; 1, vague pain; 2, mild; 3, moderate; 4, severe; 5, excruciating), haematuria (0, nil; 1, turbid; 2, cloudy; 3, reddish; 4, occasional frank blood; 5, continuous frank blood), burning sensation (0, nil; 1, minimal; 2, moderate; 3, terminal severe; 4, occasional excruciating; 5, continuous excruciating), and dysuria (0, nil; 1, minimal; 2, moderate; 3, terminal severe; 4, occasional excruciating, 5, continuous excruciating), ultrasonography for back pressure (0, nil; 1, mild; 2, moderate; 3, severe kidney and ureter; 4, unilateral total; 5, bilateral total anuria) and eight urine deposit findings (0, nil; 1, +; 2, 2+; 3, 3+; 4, 4+; 5, plenty), red blood cells, pus cells, whewellite crystals, weddellite crystals, phosphate crystals, uric acid/ammonium urate crystals, crystal clumping and crystal aggregation making a total of 13 parameters. Each parameter was given values ranging from 0 to 5. The total score was calculated and chemotherapeutic regimes were decided base on the score, which varied from 0 to 65. Hundred randomly selected patients who had been visiting the stone clinic for a minimum of five occasions were included in the study. The total scores of temporary risk were correlated with the permanent clinical risk score mentioned earlier. The temporary risk of the 100 patients during the total of 500 visits ranged from 0 to 43 out of 65. The risk score reduced significantly from visit 1 to 5 in all the patients. On correlating the mean index of the five visits with the permanent risk index, the correlation coefficient r value was +0.39 (P < 0.01). It was observed that patients go through periods of hyperactivity of stone metabolism and present with symptoms, producing temporary phases of overactivity. It is concluded that temporary risk index is correlatable with the permanent risk index of the patients forming urinary stones. It can be used as a method for scientific prediction regarding future stone formation in any individual. The dose of drugs and need for continuing chemotherapy for patients should be based on the temporary risk index. The blind prescription of drugs should be discouraged.

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Year:  2009        PMID: 19830414     DOI: 10.1007/s00240-009-0225-1

Source DB:  PubMed          Journal:  Urol Res        ISSN: 0300-5623


  15 in total

1.  Urinary calcium oxalate saturation in healthy infants and children.

Authors:  B Hoppe; A Jahnen; D Bach; A Hesse
Journal:  J Urol       Date:  1997-08       Impact factor: 7.450

2.  Urinary saturation and risk factors for calcium oxalate stone disease based on spot and 24-hour urine specimens.

Authors:  Yoshihide Ogawa; Hiroyuki Yonou; Sanehiro Hokama; Masami Oda; Makoto Morozumi; Kimio Sugaya
Journal:  Front Biosci       Date:  2003-09-01

3.  Why does the Bonn Risk Index discriminate between calcium oxalate stone formers and healthy controls?

Authors:  John P Kavanagh; Norbert Laube
Journal:  J Urol       Date:  2006-02       Impact factor: 7.450

4.  Repeated urine analysis in patients with calcium stone disease.

Authors:  H Bek-Jensen; H G Tiselius
Journal:  Eur Urol       Date:  1998       Impact factor: 20.096

5.  [Indicators of the risk of calcium oxalate urinary calculi: comparative study of the Parks' and Tiselius' indices, urinary citrate/calciuria ratio, and morning crystalluria].

Authors:  M Robert; A M Boularan; J Guiter; L Monnier
Journal:  Prog Urol       Date:  1996-04       Impact factor: 0.915

6.  Results of a prospective trial to compare normal urine supersaturation in children and adults.

Authors:  William Defoor; John Asplin; Elizabeth Jackson; Chad Jackson; Pramod Reddy; Curtis Sheldon; Eugene Minevich
Journal:  J Urol       Date:  2005-10       Impact factor: 7.450

7.  Aspects on estimation of the risk of calcium oxalate crystallization in urine.

Authors:  H G Tiselius
Journal:  Urol Int       Date:  1991       Impact factor: 2.089

8.  Determination of the calcium oxalate crystallization risk from urine samples: the BONN Risk Index in comparison to other risk formulas.

Authors:  Norbert Laube; Stefan Hergarten; Bernd Hoppe; Matthias Schmidt; Albrecht Hesse
Journal:  J Urol       Date:  2004-07       Impact factor: 7.450

9.  Idiopathic calcium oxalate urinary lithiasis: usefulness of Parks' and Tiselius' indices in the evaluation of the risk of stone formation.

Authors:  M Robert; J O Roux; A M Boularan; F Bourelly; L Monnier; D Grasset
Journal:  Urol Int       Date:  1995       Impact factor: 2.089

10.  Evaluation of the risk of stone formation: study on crystalluria in patients with recurrent calcium oxalate urolithiasis.

Authors:  M Robert; A M Boularan; O Delbos; L Monnier; D Grasset
Journal:  Eur Urol       Date:  1996       Impact factor: 20.096

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