Literature DB >> 19828413

Choroidal metastases from lung adenocarcinoma.

Paloma Martín Martorell1, José F Marí Cotino, Amelia Insa.   

Abstract

A 32-year-old woman presented with an unknown visual deficit. Fundus examination revealed a lesion compatible with a metastatic focus. Diagnostic workup revealed a lung mass and the biopsy was compatible with lung adenocarcinoma. The intraocular lesion was the only metastatic site at the time of diagnosis. She received local choroidal treatment and further systemic therapy. A pneumonectomy was performed. Five months later she progressed systemically and has since then received several lines of chemotherapy. Choroidal metastases are an infrequent site of systemic dissemination and associated with a poor prognosis, with a median survival of around 2 months if it is the first manifestation of a lung neoplasm. Here we review the literature on choroidal metastases, their treatment options and epidemiology.

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Year:  2009        PMID: 19828413     DOI: 10.1007/s12094-009-0426-7

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  6 in total

1.  Choroidal metastasis in disseminated lung cancer: frequency and risk factors.

Authors:  Klaus-Martin Kreusel; Thomas Wiegel; Marit Stange; Norbert Bornfeld; Wolfgang Hinkelbein; Michael H Foerster
Journal:  Am J Ophthalmol       Date:  2002-09       Impact factor: 5.258

2.  Decreased prevalence of asymptomatic choroidal metastasis in disseminated breast and lung cancer: argument against screening.

Authors:  A Barak; M Neudorfer; G Heilweil; O Merimsky; A Lowenstein; M Inbar; N Yaal-Hahoshen
Journal:  Br J Ophthalmol       Date:  2006-08-30       Impact factor: 4.638

3.  Choroidal metastasis: case reports and review of the literature.

Authors:  Jennifer Tsou Chong; Andrew Mick
Journal:  Optometry       Date:  2005-05

4.  External beam radiotherapy of choroidal metastases--final results of a prospective study of the German Cancer Society (ARO 95-08).

Authors:  Thomas Wiegel; Dirk Bottke; Klaus-Martin Kreusel; Stephanie Schmidt; Norbert Bornfeld; Michael H Foerster; Wolfgang Hinkelbein
Journal:  Radiother Oncol       Date:  2002-07       Impact factor: 6.280

5.  Frequency of asymptomatic choroidal metastasis in patients with disseminated breast cancer: results of a prospective screening programme.

Authors:  T Wiegel; K M Kreusel; N Bornfeld; D Bottke; M Stange; M H Foerster; W Hinkelbein
Journal:  Br J Ophthalmol       Date:  1998-10       Impact factor: 4.638

6.  Incidence and clinical characteristics of symptomatic choroidal metastasis from lung cancer.

Authors:  Klaus-Martin Kreusel; Nikolaos E Bechrakis; Thomas Wiegel; Lothar Krause; Michael H Foerster
Journal:  Acta Ophthalmol       Date:  2007-12-11       Impact factor: 3.761

  6 in total

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