| Literature DB >> 19827950 |
John D Scott1, Anna Wald, Mari Kitahata, Elizabeth Krantz, Linda Drolette, Lawrence Corey, Chia C Wang.
Abstract
This retrospective cohort study of HIV/hepatitis C virus (HCV) coinfected patients evaluated time trends and rates of HCV evaluation for patients seen between January 1, 1997 and October 30, 2004. Survival analysis and Cox proportional hazards modeling were used to describe the time to evaluation and covariates associated with this outcome. Patients were predominantly white and male. Of 248 eligible patients, 108 (44%) were evaluated for HCV treatment. The median time to evaluation was 2.98 years. Of 108 evaluated, 17 (16%) received at least one dose of interferon and/or ribavirin. The median time to treatment after being evaluated was 1.39 years. Of the 17 (35%) treated 6 patients had a sustained virologic response, but only 2.4% of the original number of patients were cured. Approximately one half of patients in an HIV-specialty clinic were evaluated for HCV therapy and 16% received treatment, but the median time to treatment from the time of HCV diagnosis was over 4 years. Further efforts to identify and to overcome barriers to HCV treatment are warranted.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19827950 PMCID: PMC2859767 DOI: 10.1089/apc.2009.0099
Source DB: PubMed Journal: AIDS Patient Care STDS ISSN: 1087-2914 Impact factor: 5.078