Literature DB >> 19827945

Long-lasting measles outbreak affecting several unrelated networks of unvaccinated persons.

Frédéric Dallaire1, Gaston De Serres, François-William Tremblay, France Markowski, Graham Tipples.   

Abstract

Despite a population immunity level estimated at approximately 95%, an outbreak of measles responsible for 94 cases occurred in Quebec, Canada. Unlike previous outbreaks in which most unvaccinated children belonged to a single community, this outbreak had cases coming from several unrelated networks of unvaccinated persons dispersed in the population. No epidemiological link was found for about one-third of laboratory-confirmed cases. This outbreak demonstrated that minimal changes in the level of aggregation of unvaccinated individuals can lead to sustained transmission in highly vaccinated populations. Mathematical work is needed regarding the level of aggregation of unvaccinated individuals that would jeopardize elimination.

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Year:  2009        PMID： 19827945     DOI： 10.1086/644783

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  14 in total

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7.  The role of vaccination coverage, individual behaviors, and the public health response in the control of measles epidemics: an agent-based simulation for California.

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8.  Measles in Canada Between 2002 and 2013.

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