Synthesis of a new spiro-BOX ligand and its application in enantioselective allylic cyclization based on carbopalladation of allenyl hydrazines.

In this paper, we developed a new bisoxazoline ligand with a spiro skeleton and a alpha-naphthylmethyl substituent, i.e. (Ra,S,S)-L3, which has been successfully applied to the highly enantioselective cyclic allylation based on the carbopalladation of 3,4-allenyl hydrazines with ee values ranging from 92-95%.