Literature DB >> 19825398

Ocotea quixos Lam. essential oil: in vitro and in vivo investigation on its anti-inflammatory properties.

Vigilio Ballabeni1, Massimiliano Tognolini, Carmine Giorgio, Simona Bertoni, Renato Bruni, Elisabetta Barocelli.   

Abstract

Here we investigated the anti-inflammatory properties of Ocotea quixos essential oil and of its main components, trans-cinnamaldehyde and methyl cinnamate, in in vitro and in vivo models. Ocotea essential oil and trans-cinnamaldehyde but not methyl cinnamate significantly reduced LPS-induced NO release from J774 macrophages at non-toxic concentrations, inhibited LPS-induced COX-2 expression and increased forskolin-induced cAMP production. The essential oil (30-100mg/kg os) and trans-cinnamaldehyde (10mg/kg os) in carrageenan-induced rat paw edema showed anti-inflammatory effect without damaging gastric mucosa. In conclusion we provide the first evidence of a significant anti-inflammatory gastro-sparing activity of O.quixos essential oil. (c) 2009 Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 19825398     DOI： 10.1016/j.fitote.2009.10.002

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  7 in total

1.  Trans-Cinnamaldehyde, An Essential Oil in Cinnamon Powder, Ameliorates Cerebral Ischemia-Induced Brain Injury via Inhibition of Neuroinflammation Through Attenuation of iNOS, COX-2 Expression and NFκ-B Signaling Pathway.

Authors:  Yuh-Fung Chen; Yu-Wen Wang; Wei-Shih Huang; Ming-Ming Lee; W Gibson Wood; Yuk-Man Leung; Huei-Yann Tsai
Journal:  Neuromolecular Med       Date:  2016-04-18       Impact factor: 3.843

Review 2.  Efficacy of trans-cinnamaldehyde against Psoroptes cuniculi in vitro.

Authors:  Fengge Shen; Mingxun Xing; Lihui Liu; Xudong Tang; Wei Wang; Xiaohong Wang; Xiuping Wu; Xuelin Wang; Xinrui Wang; Guangming Wang; Junhui Zhang; Lei Li; Jiyu Zhang; Lu Yu
Journal:  Parasitol Res       Date:  2012-02-15       Impact factor: 2.289

3.  Essential Oils of Gardenia jasminoides J. Ellis and Gardenia jasminoides f. longicarpa Z.W. Xie & M. Okada Flowers: Chemical Characterization and Assessment of Anti-Inflammatory Effects in Alveolar Macrophage.

Authors:  Nan Zhang; Ying Bian; Lei Yao
Journal:  Pharmaceutics       Date:  2022-04-29       Impact factor: 6.525

4.  Trans-cinnamaldehyde protected PC12 cells against oxygen and glucose deprivation/reperfusion (OGD/R)-induced injury via anti-apoptosis and anti-oxidative stress.

Authors:  Xue Qi; Ru Zhou; Yue Liu; Jing Wang; Wan-Nian Zhang; Huan-Ran Tan; Yang Niu; Tao Sun; Yu-Xiang Li; Jian-Qiang Yu
Journal:  Mol Cell Biochem       Date:  2016-08-16       Impact factor: 3.396

5.  Ferulic acid ethyl ester diminished Complete Freund's Adjuvant-induced incapacitation through antioxidant and anti-inflammatory activity.

Authors:  Francisco Valmor Macedo Cunha; Bruno de Sousa Gomes; Benedito de Sousa Neto; Alana Rodrigues Ferreira; Damião Pergentino de Sousa; Maria do Carmo de Carvalho e Martins; Francisco de Assis Oliveira
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2015-10-24       Impact factor: 3.000

6.  Chemical Diversity, Biological Activity, and Genetic Aspects of Three Ocotea Species from the Amazon.

Authors:  Joyce Kelly da Silva; Rafaela da Trindade; Edith Cibelle Moreira; José Guilherme S Maia; Noura S Dosoky; Rebecca S Miller; Leland J Cseke; William N Setzer
Journal:  Int J Mol Sci       Date:  2017-05-18       Impact factor: 5.923

Review 7.  A review on anti-inflammatory activity of phenylpropanoids found in essential oils.

Authors:  Rita de Cássia da Silveira E Sá; Luciana Nalone Andrade; Rafael Dos Reis Barreto de Oliveira; Damião Pergentino de Sousa
Journal:  Molecules       Date:  2014-01-27       Impact factor: 4.411
  7 in total

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