OBJECTIVE: To evaluate the frequency and clinical correlates of adult separation anxiety disorder in a large cohort of patients with mood and anxiety disorders. METHOD: Overall, 508 outpatients with anxiety and mood disorders were assessed by the structured clinical interview for diagnostic and statistical manual (IV edition) axis I disorders for principal diagnosis and comorbidity and by other appropriate instruments for separation anxiety into adulthood or childhood. RESULTS: Overall, 105 subjects (20.7%) were assessed as having adult separation anxiety disorder without a history of childhood separation anxiety and 110 (21.7%) had adult separation anxiety disorder with a history of childhood separation anxiety. Adult separation anxiety was associated with severe role impairment in work and social relationships after controlling for potential confounding effect of anxiety comorbidity. CONCLUSION: Adult separation anxiety disorder is likely to be much more common in adults than previously recognized. Research is needed to better understand the relationships of this condition with other co-occurring affective disorders.
OBJECTIVE: To evaluate the frequency and clinical correlates of adult separation anxiety disorder in a large cohort of patients with mood and anxiety disorders. METHOD: Overall, 508 outpatients with anxiety and mood disorders were assessed by the structured clinical interview for diagnostic and statistical manual (IV edition) axis I disorders for principal diagnosis and comorbidity and by other appropriate instruments for separation anxiety into adulthood or childhood. RESULTS: Overall, 105 subjects (20.7%) were assessed as having adult separation anxiety disorder without a history of childhood separation anxiety and 110 (21.7%) had adult separation anxiety disorder with a history of childhood separation anxiety. Adult separation anxiety was associated with severe role impairment in work and social relationships after controlling for potential confounding effect of anxiety comorbidity. CONCLUSION: Adult separation anxiety disorder is likely to be much more common in adults than previously recognized. Research is needed to better understand the relationships of this condition with other co-occurring affective disorders.
Authors: Derrick Silove; Jordi Alonso; Evelyn Bromet; Mike Gruber; Nancy Sampson; Kate Scott; Laura Andrade; Corina Benjet; Jose Miguel Caldas de Almeida; Giovanni De Girolamo; Peter de Jonge; Koen Demyttenaere; Fabian Fiestas; Silvia Florescu; Oye Gureje; Yanling He; Elie Karam; Jean-Pierre Lepine; Sam Murphy; Jose Villa-Posada; Zahari Zarkov; Ronald C Kessler Journal: Am J Psychiatry Date: 2015-06-05 Impact factor: 18.112
Authors: D Lizardi; M F Grunebaum; A Burke; B Stanley; J J Mann; J Harkavy-Friedman; M Oquendo Journal: Acta Psychiatr Scand Date: 2011-06-03 Impact factor: 6.392
Authors: Gino Pozzi; Angelo Bruschi; Andrea De Angelis; Marco Pascucci; Daniele Stavros Hatzigiakoumis; Paolo Grandinetti; Marco Di Nicola; Stefano Pini; Luigi Janiri Journal: Biomed Res Int Date: 2014-07-03 Impact factor: 3.411