INTRODUCTION: Developmental dyslexia has been associated with reduced interhemispheric neural connectivity in children. The present study investigated functional interhemispheric connectivity in male dyslexic adults. METHODS: A group of 19 dyslexic men were compared to a group of 15 controls on interhemispheric coherence of the dominant frequency in the power spectrum during a visuo-spatial attention task. The coherence between a left hemisphere central-parietal electrode and the respective right hemisphere electrode and surrounding sites was analysed. RESULTS: Compared to controls, the dyslexic group demonstrated reduced, and more diffuse, interhemispheric coherence of alpha activity in the central-parietal cortex. No group differences in interhemispheric coherence were found on frontal, temporal or central sites. CONCLUSIONS: The deviant pattern of functional connectivity in dyslexics is suggestive of an altered development of neural circuitry that may lead to deficits in magnocellular processing. Copyright (c) 2009 Elsevier Srl. All rights reserved.
INTRODUCTION:Developmental dyslexia has been associated with reduced interhemispheric neural connectivity in children. The present study investigated functional interhemispheric connectivity in male dyslexic adults. METHODS: A group of 19 dyslexic men were compared to a group of 15 controls on interhemispheric coherence of the dominant frequency in the power spectrum during a visuo-spatial attention task. The coherence between a left hemisphere central-parietal electrode and the respective right hemisphere electrode and surrounding sites was analysed. RESULTS: Compared to controls, the dyslexic group demonstrated reduced, and more diffuse, interhemispheric coherence of alpha activity in the central-parietal cortex. No group differences in interhemispheric coherence were found on frontal, temporal or central sites. CONCLUSIONS: The deviant pattern of functional connectivity in dyslexics is suggestive of an altered development of neural circuitry that may lead to deficits in magnocellular processing. Copyright (c) 2009 Elsevier Srl. All rights reserved.
Authors: T Sigi Hale; Susan L Smalley; Patricia D Walshaw; Grant Hanada; James Macion; James T McCracken; James J McGough; Sandra K Loo Journal: Neuropsychologia Date: 2010-08-10 Impact factor: 3.139
Authors: Kathleen Kay Amora; Ariane Tretow; Cara Verwimp; Jurgen Tijms; Paavo H T Leppänen; Valéria Csépe Journal: Front Neurosci Date: 2022-06-30 Impact factor: 5.152
Authors: Scott L Brincat; Jacob A Donoghue; Meredith K Mahnke; Simon Kornblith; Mikael Lundqvist; Earl K Miller Journal: Neuron Date: 2021-02-08 Impact factor: 18.688
Authors: Gorka Fraga González; Dirk J A Smit; Melle J W van der Molen; Jurgen Tijms; Cornelis Jan Stam; Eco J C de Geus; Maurits W van der Molen Journal: Front Hum Neurosci Date: 2018-08-30 Impact factor: 3.169
Authors: Gorka Fraga-González; Dirk J A Smit; Melle J W Van der Molen; Jurgen Tijms; Cornelis J Stam; Eco J C de Geus; Maurits W Van der Molen Journal: Front Psychol Date: 2021-11-19