Literature DB >> 19822143

Membrane microdomains and insulin resistance.

Jin-ichi Inokuchi1.   

Abstract

A new concept, that "metabolic disorders, such as type 2 diabetes, are membrane microdomain disorders caused by aberrant expression of gangliosides", has arisen. By examining this working hypothesis, we demonstrate the molecular pathogenesis of type 2 diabetes and insulin resistance focusing on the interaction between insulin receptor and gangliosides in microdomains and propose the new therapeutic strategy "membrane microdomain ortho-signaling therapy". Copyright 2009 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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Year:  2009        PMID： 19822143     DOI： 10.1016/j.febslet.2009.10.012

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  24 in total

Review 1.  Structures, biosynthesis, and functions of gangliosides--an overview.

Authors:  Robert K Yu; Yi-Tzang Tsai; Toshio Ariga; Makoto Yanagisawa
Journal:  J Oleo Sci       Date:  2011       Impact factor: 1.601

Review 2.  Spatial organization of transmembrane receptor signalling.

Authors:  Ioanna Bethani; Sigrid S Skånland; Ivan Dikic; Amparo Acker-Palmer
Journal:  EMBO J       Date:  2010-08-18       Impact factor: 11.598

Review 3.  Glycosphingolipid functions.

Authors:  Clifford A Lingwood
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-07-01       Impact factor: 10.005

4.  Altered expression of ganglioside GM3 molecular species and a potential regulatory role during myoblast differentiation.

Authors:  Shinji Go; Shiori Go; Lucas Veillon; Maria Grazia Ciampa; Laura Mauri; Chihiro Sato; Ken Kitajima; Alessandro Prinetti; Sandro Sonnino; Jin-Ichi Inokuchi
Journal:  J Biol Chem       Date:  2017-03-08       Impact factor: 5.157

Review 5.  Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach.

Authors:  Pallavi Asthana; Joaquim Si Long Vong; Gajendra Kumar; Raymond Chuen-Chung Chang; Gang Zhang; Kazim A Sheikh; Chi Him Eddie Ma
Journal:  Mol Neurobiol       Date:  2015-09-15       Impact factor: 5.590

Review 6.  The twists and turns of sphingolipid pathway in glucose regulation.

Authors:  Gergana M Deevska; Mariana N Nikolova-Karakashian
Journal:  Biochimie       Date:  2010-05-31       Impact factor: 4.079

Review 7.  The challenge and promise of glycomics.

Authors:  Richard D Cummings; J Michael Pierce
Journal:  Chem Biol       Date:  2014-01-16

Review 8.  Insulin resistance: a connecting link between Alzheimer's disease and metabolic disorder.

Authors:  Viplav Kshirsagar; Chetan Thingore; Archana Juvekar
Journal:  Metab Brain Dis       Date:  2020-09-28       Impact factor: 3.584

Review 9.  Sphingolipid signaling in metabolic disorders.

Authors:  Timothy Hla; Andrew J Dannenberg
Journal:  Cell Metab       Date:  2012-09-13       Impact factor: 27.287

10.  Trimeric Tn antigen on syndecan 1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin α5β1 and matrix metalloproteinase 9.

Authors:  Yasuyuki Matsumoto; Qing Zhang; Kaoru Akita; Hiroshi Nakada; Kazunori Hamamura; Akiko Tsuchida; Tetsuya Okajima; Keiko Furukawa; Takeshi Urano; Koichi Furukawa
Journal:  J Biol Chem       Date:  2013-06-27       Impact factor: 5.157
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