Literature DB >> 1982083

[GABAergic modulation of amnesic trace reproduction by activation of the dopaminergic system].

N I Dubrovina, R I Parkhomenko, R Iu Il'iuchenok.   

Abstract

Features of amnesia trace reactivation by activation of different links of dopaminergic system synaptic apparatus following the change of benzodiazepine, GABAA and GABAB receptors activity are found in experiments in mice. Diazepam pretreatment increases bupropion effectiveness, prolongs duration of enhanced passive avoidance response retrieval during D-1 and D-2 receptors activation by (+)3-PPP and decreases both characteristics under selective D-2 receptor activation by quinpirole. Activation of GABAA and GABAB receptors induces the attenuation of quinpirole effect and the duration of (+)3-PPP action.

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Year:  1990        PMID: 1982083

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN: 0365-9615


  1 in total

1.  Contribution of presynaptic dopaminergic receptors to the mechanism of the reactivating effects of blockade of the GABA-benzodiazepine-ionophore complex.

Authors:  N I Dubrovina; R Y Il'yuchenok
Journal:  Neurosci Behav Physiol       Date:  1998 May-Jun
  1 in total

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