Literature DB >> 198205

Toxicological properties of lead.

T Damstra.   

Abstract

The pathological effects of lead on the renal, nervous, reproductive, endocrine, and immune systems have been reviewed. Emphasis is placed on reported subclinical effects due to chronic, low-level lead exposure. The crucial issue of whether subtle behavioral, intellectual, and developmental impairment occurs in young children, as a result of lead-induced CNS damage is discussed in detail. This issue remains unresolved. Further studies are needed in order to determine the long-term health effects of continuous, low-level lead exposure.

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Year:  1977        PMID: 198205      PMCID: PMC1637416          DOI: 10.1289/ehp.7719297

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  83 in total

1.  Evaluation of the humoral immune response of children with low lead exposure.

Authors:  J R Reigart; C D Graber
Journal:  Bull Environ Contam Toxicol       Date:  1976-07       Impact factor: 2.151

2.  Proceedings: Environmental lead: a survey of its possible physiological significance.

Authors:  H V Warren
Journal:  J Biosoc Sci       Date:  1974-04

3.  Lead-induced behavioral dysfunction: an animal model of hyperactivity.

Authors:  E K Silbergeld; A M Goldberg
Journal:  Exp Neurol       Date:  1974-01       Impact factor: 5.330

4.  An improved model of lead-induced brain dysfunction in the suckling rat.

Authors:  I A Michaelson; M W Sauerhoff
Journal:  Toxicol Appl Pharmacol       Date:  1974-04       Impact factor: 4.219

5.  Neuropathologic changes produced in suckling mice by adding lead to the maternal diet.

Authors:  W I Rosenblum; M G Johnson
Journal:  Arch Pathol       Date:  1968-06

6.  Induction of cerebral gliomas in rats with dietary lead subacetate and 2-acetylaminofluorene.

Authors:  R Oyasu; H A Battifora; R A Clasen; J H McDonald; G M Hass
Journal:  Cancer Res       Date:  1970-05       Impact factor: 12.701

7.  Pica and elevated blood lead level in autistic and atypical children.

Authors:  D J Cohen; W T Johnson; B K Caparulo
Journal:  Am J Dis Child       Date:  1976-01

8.  Increased lead absorption with anemia and slowed nerve conduction in children near a lead smelter.

Authors:  P J Landrigan; E L Baker; R G Feldman; D H Cox; K V Eden; W A Orenstein; J A Mather; A J Yankel; I H Von Lindern
Journal:  J Pediatr       Date:  1976-12       Impact factor: 4.406

9.  Follow-up of children overexposed to lead.

Authors:  R E Albert; R E Shore; A J Sayers; C Strehlow; T J Kneip; B S Pasternack; A J Friedhoff; F Covan; J A Cimino
Journal:  Environ Health Perspect       Date:  1974-05       Impact factor: 9.031

10.  Development of behavioral tests for the assessment of neurologic effects of lead in sheep.

Authors:  T L Carson; G A Van Gelder; G G Karas; W B Buck
Journal:  Environ Health Perspect       Date:  1974-05       Impact factor: 9.031

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  14 in total

1.  Effects of Cu(2+), Pb (2+) and Zn (2+) on voltage-activated currents in Helix pomatia L. Neurons.

Authors:  O N Osipenko; T Kiss; J Salánki
Journal:  Environ Monit Assess       Date:  1992-07       Impact factor: 2.513

2.  Modulation of synaptic events by heavy metals in the central nervous system of mollusks.

Authors:  K Rózsa; J Salánki
Journal:  Cell Mol Neurobiol       Date:  1994-12       Impact factor: 5.046

3.  Low-dose lead encephalopathy in the suckling rat.

Authors:  R Sundström; N G Conradi; P Sourander
Journal:  Acta Neuropathol       Date:  1983       Impact factor: 17.088

4.  Splenomegaly and adrenal weight changes in isolated adult mice chronically exposed to lead.

Authors:  D M Ogilvie; A H Martin
Journal:  Bull Environ Contam Toxicol       Date:  1981-05       Impact factor: 2.151

5.  Biochemical effects of lead exposure on battery manufacture workers with reference to blood pressure, calcium metabolism and bone mineral density.

Authors:  Nilima N Dongre; Adinath N Suryakar; Arun J Patil; Indira A Hundekari; Basavaraj B Devarnavadagi
Journal:  Indian J Clin Biochem       Date:  2012-07-27

6.  Pb2+ modulates the NMDA-receptor-channel complex.

Authors:  V Uteshev; D Büsselberg; H L Haas
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-02       Impact factor: 3.000

7.  Effects of Etlingera elatior extracts on lead acetate-induced testicular damage: A morphological and biochemical study.

Authors:  Khor Yen Haw; Srikumar Chakravarthi; Nagaraja Haleagrahara; Mallikarjuna Rao
Journal:  Exp Ther Med       Date:  2011-09-21       Impact factor: 2.447

8.  Aggression and open-field activity of lead-exposed mice.

Authors:  D M Ogilvie; A H Martin
Journal:  Arch Environ Contam Toxicol       Date:  1982       Impact factor: 2.804

9.  Peripheral blood signatures of lead exposure.

Authors:  Heather G LaBreche; Sarah K Meadows; Joseph R Nevins; John P Chute
Journal:  PLoS One       Date:  2011-08-01       Impact factor: 3.240

Review 10.  Indices of potential lead hazard.

Authors:  H S Posner
Journal:  Environ Health Perspect       Date:  1977-08       Impact factor: 9.031

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