Literature DB >> 19820426

Twin preterm neonates with cardiac toxicity related to lopinavir/ritonavir therapy.

Monica A McArthur1, Stella U Kalu, Arlen R Foulks, Ashraf M Aly, Sunil K Jain, Janak A Patel.   

Abstract

We report twin neonates who were born prematurely at 32 weeks of gestation to a mother with human immunodeficiency virus infection. One of the twins developed complete heart block and dilated cardiomyopathy related to lopinavir/ritonavir therapy, a boosted protease-inhibitor agent, while the other twin developed mild bradycardia. We recommend caution in the use of lopinavir/ritonavir in the immediate neonatal period.

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Year:  2009        PMID： 19820426     DOI： 10.1097/INF.0b013e3181acd17e

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  11 in total

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