Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Role of HDAC1 in senescence, aging, and cancer.

Literature DB >> 19818845

Role of HDAC1 in senescence, aging, and cancer.

Danielle Willis-Martinez¹, Hunter W Richards, Nikolai A Timchenko, Estela E Medrano.

Abstract

HDAC1 is a member of the class I of histone deacetylases that also includes HDAC2, -3 and -8. Although HDAC1 has been mostly studied in the context of cancer, recent evidence strongly suggests that it plays critical roles in cellular senescence, aging of the liver, myelination, and adult neurogenesis. Here we review such roles and discuss the entangled relationships between HDAC1 with histone acetyltransferases and other HDACs including SIRT1. 2009 Elsevier Inc. All rights reserved.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19818845 PMCID： PMC2838962 DOI： 10.1016/j.exger.2009.10.001

Source DB: PubMed Journal: Exp Gerontol ISSN： 0531-5565 Impact factor: 4.032

60 in total

Review 1. Liver regeneration.

Authors: George K Michalopoulos
Journal: J Cell Physiol Date: 2007-11 Impact factor: 6.384

2. ING1a expression increases during replicative senescence and induces a senescent phenotype.

Authors: Mohamed A Soliman; Philip Berardi; Svitlana Pastyryeva; Paul Bonnefin; Xiaolan Feng; Ana Colina; Dallan Young; Karl Riabowol
Journal: Aging Cell Date: 2008-09-16 Impact factor: 9.304

3. Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.

Authors: Yoshihiro Dohi; Tsuyoshi Ikura; Yutaka Hoshikawa; Yasutake Katoh; Kazushige Ota; Ayako Nakanome; Akihiko Muto; Shinji Omura; Tsutomu Ohta; Akihiro Ito; Minoru Yoshida; Tetsuo Noda; Kazuhiko Igarashi
Journal: Nat Struct Mol Biol Date: 2008-11-16 Impact factor: 15.369

4. Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation.

Authors: Yong-Hak Seo; Hyun-Jung Jung; Hyun-Taek Shin; You-Mie Kim; Hyunee Yim; Hae-Young Chung; In Kyoung Lim; Gyesoon Yoon
Journal: Aging Cell Date: 2008-09-08 Impact factor: 9.304

Review 5. HDAC family: What are the cancer relevant targets?

Authors: Olaf Witt; Hedwig E Deubzer; Till Milde; Ina Oehme
Journal: Cancer Lett Date: 2008-09-27 Impact factor: 8.679

Review 6. Epigenetic marks in melanoma.

Authors: Hunter W Richards; Estela E Medrano
Journal: Pigment Cell Melanoma Res Date: 2008-11-27 Impact factor: 4.693

7. HDAC1 cooperates with C/EBPalpha in the inhibition of liver proliferation in old mice.

Authors: Guo-Li Wang; Elizabeth Salisbury; Xiurong Shi; Lubov Timchenko; Estela E Medrano; Nikolai A Timchenko
Journal: J Biol Chem Date: 2008-07-11 Impact factor: 5.157

8. Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.

Authors: Dohoon Kim; Christopher L Frank; Matthew M Dobbin; Rachel K Tsunemoto; Weihong Tu; Peter L Peng; Ji-Song Guan; Byung-Hoon Lee; Lily Y Moy; Paola Giusti; Nisha Broodie; Ralph Mazitschek; Ivanna Delalle; Stephen J Haggarty; Rachael L Neve; Youming Lu; Li-Huei Tsai
Journal: Neuron Date: 2008-12-10 Impact factor: 17.173

9. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

Authors: Xiaohua Shen; Yingchun Liu; Yu-Jung Hsu; Yuko Fujiwara; Jonghwan Kim; Xiaohong Mao; Guo-Cheng Yuan; Stuart H Orkin
Journal: Mol Cell Date: 2008-11-21 Impact factor: 17.970

10. Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.

Authors: Raphael Margueron; Guohong Li; Kavitha Sarma; Alexandre Blais; Jiri Zavadil; Christopher L Woodcock; Brian D Dynlacht; Danny Reinberg
Journal: Mol Cell Date: 2008-11-21 Impact factor: 17.970

32 in total

1. The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation.

Authors: Jingling Jin; Polina Iakova; Yanjun Jiang; Estela E Medrano; Nikolai A Timchenko
Journal: Hepatology Date: 2011-07-27 Impact factor: 17.425

Review 2. Epigenetic biomarkers in skin cancer.

Authors: Edward S Greenberg; Kelly K Chong; Kelly T Huynh; Ryo Tanaka; Dave S B Hoon
Journal: Cancer Lett Date: 2012-01-27 Impact factor: 8.679

Review 3. Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?

Authors: Diana Crossley; Robert Stockley; Elizabeth Sapey
Journal: Drugs Aging Date: 2019-09 Impact factor: 3.923

4. Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice.

Authors: Janitza L Montalvo-Ortiz; Daniel W Fisher; Guadalupe Rodríguez; Deyu Fang; John G Csernansky; Hongxin Dong
Journal: Psychopharmacology (Berl) Date: 2017-04-18 Impact factor: 4.530

5. Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver.

Authors: Irina M Bochkis; Dariusz Przybylski; Jenny Chen; Aviv Regev
Journal: Cell Rep Date: 2014-10-23 Impact factor: 9.423

6. Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction.

Authors: Jin-Ying Lu; Yu-Yi Lin; Jin-Chuan Sheu; June-Tai Wu; Fang-Jen Lee; Yue Chen; Min-I Lin; Fu-Tien Chiang; Tong-Yuan Tai; Shelley L Berger; Yingming Zhao; Keh-Sung Tsai; Heng Zhu; Lee-Ming Chuang; Jef D Boeke
Journal: Cell Date: 2011-09-09 Impact factor: 41.582

7. Histone deacetylase 1 and 2 are essential for murine neural crest proliferation, pharyngeal arch development, and craniofacial morphogenesis.

Authors: Zachary J Milstone; Grace Lawson; Chinmay M Trivedi
Journal: Dev Dyn Date: 2017-09-05 Impact factor: 3.780

8. Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster.

Authors: Hongjun Zhang; Yishi Li; Junsheng Yang; Kaoru Tominaga; Olivia M Pereira-Smith; John Tower
Journal: Exp Gerontol Date: 2010-06-23 Impact factor: 4.032

9. Overexpression of histone deacetylase 2 predicts unfavorable prognosis in human gallbladder carcinoma.

Authors: Xilin Du; Huadong Zhao; Li Zang; Nuan Song; Tao Yang; Rui Dong; Jikai Yin; Chengguo Wang; Jianguo Lu
Journal: Pathol Oncol Res Date: 2012-12-16 Impact factor: 3.201

Review 10. Metabolism, longevity and epigenetics.

Authors: Claudia Cosentino; Raul Mostoslavsky
Journal: Cell Mol Life Sci Date: 2013-03-07 Impact factor: 9.261