Literature DB >> 19818632

CRL4s: the CUL4-RING E3 ubiquitin ligases.

Sarah Jackson1, Yue Xiong.   

Abstract

The evolutionarily conserved cullin family proteins can assemble as many as 400 distinct E3 ubiquitin ligase complexes that regulate diverse cellular pathways. CUL4, one of three founding cullins conserved from yeast to humans, uses a large beta-propeller protein, DDB1, as a linker to interact with a subset of WD40 proteins that serve as substrate receptors, forming as many as 90 E3 complexes in mammals. Many CRL4 complexes are involved in chromatin regulation and are frequently hijacked by different viruses.

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Year:  2009        PMID： 19818632      PMCID： PMC2783741          DOI： 10.1016/j.tibs.2009.07.002

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  100 in total

Review 1.  Mechanisms underlying ubiquitination.

Authors:  C M Pickart
Journal:  Annu Rev Biochem       Date:  2001       Impact factor: 23.643

2.  The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.

Authors:  Regina Groisman; Jolanta Polanowska; Isao Kuraoka; Jun-ichi Sawada; Masafumi Saijo; Ronny Drapkin; Alexei F Kisselev; Kiyoji Tanaka; Yoshihiro Nakatani
Journal:  Cell       Date:  2003-05-02       Impact factor: 41.582

3.  Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms.

Authors:  Cong Liu; Kelly A Powell; Kirsten Mundt; LeJung Wu; Antony M Carr; Thomas Caspari
Journal:  Genes Dev       Date:  2003-04-14       Impact factor: 11.361

4.  The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5.

Authors:  J Andrejeva; E Poole; D F Young; S Goodbourn; R E Randall
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

5.  Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.

Authors:  Ning Zheng; Brenda A Schulman; Langzhou Song; Julie J Miller; Philip D Jeffrey; Ping Wang; Claire Chu; Deanna M Koepp; Stephen J Elledge; Michele Pagano; Ronald C Conaway; Joan W Conaway; J Wade Harper; Nikola P Pavletich
Journal:  Nature       Date:  2002-04-18       Impact factor: 49.962

6.  De-etiolated 1 and damaged DNA binding protein 1 interact to regulate Arabidopsis photomorphogenesis.

Authors:  Dana F Schroeder; Manfred Gahrtz; Bridey B Maxwell; R Kimberley Cook; Jack M Kan; José M Alonso; Joseph R Ecker; Joanne Chory
Journal:  Curr Biol       Date:  2002-09-03       Impact factor: 10.834

7.  CUL-4A is critical for early embryonic development.

Authors:  Binghui Li; Joseph C Ruiz; Kristin T Chun
Journal:  Mol Cell Biol       Date:  2002-07       Impact factor: 4.272

8.  Hepatitis B virus X protein and simian virus 5 V protein exhibit similar UV-DDB1 binding properties to mediate distinct activities.

Authors:  Olivier Leupin; Séverine Bontron; Michel Strubin
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

9.  Characterization of a Schizosaccharomyces pombe strain deleted for a sequence homologue of the human damaged DNA binding 1 (DDB1) gene.

Authors:  Francesca Zolezzi; Jill Fuss; Satoru Uzawa; Stuart Linn
Journal:  J Biol Chem       Date:  2002-08-13       Impact factor: 5.157

10.  Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components.

Authors:  Christina M Ulane; Curt M Horvath
Journal:  Virology       Date:  2002-12-20       Impact factor: 3.616
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  192 in total

1.  Proliferating cell nuclear antigen-dependent rapid recruitment of Cdt1 and CRL4Cdt2 at DNA-damaged sites after UV irradiation in HeLa cells.

Authors:  Takashi Ishii; Yasushi Shiomi; Toshihiro Takami; Yusuke Murakami; Naho Ohnishi; Hideo Nishitani
Journal:  J Biol Chem       Date:  2010-10-07       Impact factor: 5.157

2.  The cullin-4 complex DCDC does not require E3 ubiquitin ligase elements to control heterochromatin in Neurospora crassa.

Authors:  Keyur K Adhvaryu; Jordan D Gessaman; Shinji Honda; Zachary A Lewis; Paula L Grisafi; Eric U Selker
Journal:  Eukaryot Cell       Date:  2014-10-31

3.  Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response.

Authors:  Jayme Salsman; Madhav Jagannathan; Patrick Paladino; Pak-Kei Chan; Graham Dellaire; Brian Raught; Lori Frappier
Journal:  J Virol       Date:  2011-11-09       Impact factor: 5.103

4.  MicroRNA transgene overexpression complements deficiency-based modifier screens in Drosophila.

Authors:  Sébastien Szuplewski; Jan-Michael Kugler; Sing Fee Lim; Pushpa Verma; Ya-Wen Chen; Stephen M Cohen
Journal:  Genetics       Date:  2011-11-17       Impact factor: 4.562

Review 5.  Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy.

Authors:  Tomoaki Tanaka; Tatsuya Nakatani; Tetsu Kamitani
Journal:  Mol Oncol       Date:  2012-01-21       Impact factor: 6.603

6.  WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins.

Authors:  Natasha Pashkova; Lokesh Gakhar; Stanley C Winistorfer; Liping Yu; S Ramaswamy; Robert C Piper
Journal:  Mol Cell       Date:  2010-11-12       Impact factor: 17.970

7.  Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.

Authors:  Wei-Wei Pan; Jian-Jie Zhou; Chao Yu; Ying Xu; Lian-Jun Guo; Hai-Yi Zhang; Dawang Zhou; Fang-Zhou Song; Heng-Yu Fan
Journal:  J Biol Chem       Date:  2013-08-30       Impact factor: 5.157

8.  MSI4/FVE interacts with CUL4-DDB1 and a PRC2-like complex to control epigenetic regulation of flowering time in Arabidopsis.

Authors:  Maghsoud Pazhouhandeh; Jean Molinier; Alexandre Berr; Pascal Genschik
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-31       Impact factor: 11.205

9.  A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase.

Authors:  Sufang Zhang; Hong Zhao; Zbiegniew Darzynkiewicz; Pengbo Zhou; Zhongtao Zhang; Ernest Y C Lee; Marietta Y W T Lee
Journal:  J Biol Chem       Date:  2013-08-02       Impact factor: 5.157

10.  A MicroRNA Derived from Adenovirus Virus-Associated RNAII Promotes Virus Infection via Posttranscriptional Gene Silencing.

Authors:  K Wakabayashi; M Machitani; M Tachibana; F Sakurai; H Mizuguchi
Journal:  J Virol       Date:  2019-01-04       Impact factor: 5.103
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