Literature DB >> 1981815

The application of oligonucleotide probes to HLA class II typing of the DRB sub-region.

R W Vaughan1, J S Lanchbury, S G Marsh, M A Hall, J G Bodmer, K I Welsh.   

Abstract

A plan for DRB typing at the sequence level is detailed. Only one polymerase chain amplification reaction is needed and the application of a limited number of short oligonucleotide probes allows an almost complete definition of DRB alleles. The scheme was tested on 40 homozygous cell-lines selected to cover a wide range of specificities, and 40 RFLP-typed controls. The results are presented and discussed. The simplicity and accuracy of this scheme are emphasized.

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Year:  1990        PMID： 1981815     DOI： 10.1111/j.1399-0039.1990.tb01821.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  9 in total

1.  Analysis of the contribution of HLA genes to genetic predisposition in inflammatory bowel disease.

Authors:  I Naom; J Lee; D Ford; S J Bowman; J S Lanchbury; I Haris; S V Hodgson; D Easton; J Lennard-Jones; C G Mathew
Journal:  Am J Hum Genet       Date:  1996-07       Impact factor: 11.025

Review 2.  Major histocompatibility complex class II genes and systemic sclerosis.

Authors:  D Briggs; K I Welsh
Journal:  Ann Rheum Dis       Date:  1991-11       Impact factor: 19.103

3.  Decreased T cell precursor frequencies to Epstein-Barr virus glycoprotein Gp110 in peripheral blood correlate with disease activity and severity in patients with rheumatoid arthritis.

Authors:  E Toussirot; D Wendling; P Tiberghien; J Luka; J Roudier
Journal:  Ann Rheum Dis       Date:  2000-07       Impact factor: 19.103

4.  Gold induced nephropathy in rheumatoid arthritis and HLA class II genes.

Authors:  L I Sakkas; I C Chikanza; R W Vaughan; K I Welsh; G S Panayi
Journal:  Ann Rheum Dis       Date:  1993-04       Impact factor: 19.103

5.  Examination of HLA-DR4 as a severity marker for rheumatoid arthritis in Greek patients.

Authors:  K A Boki; A A Drosos; A G Tzioufas; J S Lanchbury; G S Panayi; H M Moutsopoulos
Journal:  Ann Rheum Dis       Date:  1993-07       Impact factor: 19.103

6.  An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele.

Authors:  D G Forcione; B Sands; K J Isselbacher; A Rustgi; D K Podolsky; S Pillai
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

7.  HLA-DR typing for kidney transplants: advantage of polymerase chain reaction with sequence specific primers in a routine hospital laboratory.

Authors:  C Lynas; N J Hurlock; J A Copplestone; A G Prentice; R J McGonigle
Journal:  J Clin Pathol       Date:  1994-07       Impact factor: 3.411

8.  Molecular heterogeneity of autosomal dominant cerebellar ataxia: analysis of flanking microsatellites of the spinocerebellar ataxia 1 locus in a northern European family unequivocally demonstrates non-linkage.

Authors:  A Lunkes; S Gispert; J Enczmann; G Auburger
Journal:  Hum Genet       Date:  1993-05       Impact factor: 4.132

9.  Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor alpha with human IDDM.

Authors:  A Cox; A M Gonzalez; A G Wilson; R M Wilson; J D Ward; C M Artlett; K Welsh; G W Duff
Journal:  Diabetologia       Date:  1994-05       Impact factor: 10.122
  9 in total

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