Literature DB >> 19816669

[Importance of hypothermia in multiple trauma patients].

F Hildebrand1, C Probst, M Frink, S Huber-Wagner, C Krettek.   

Abstract

Multiple trauma patients frequently demonstrate a hypothermic core temperature, defined as a temperature below 35 degrees C, already at admission in the emergency room. As a drop of the core temperature below 34 degrees C has been shown to be associated with a significant increase in post-traumatic complications, this limit is considered to be critical in these patients. Multiple trauma patients with hypothermia demonstrate a markedly increased mortality rate compared to normothermic patients with the same injury severity. Therefore effective rewarming measures are essential for adequate bleeding control and successful resuscitation. If and to what extent the induction of controlled hypothermia in the early phase of treatment on the intensive care unit after resuscitation and operative bleeding control can contribute to an improved post-traumatic outcome, has to be clarified in further experimental and clinical studies.

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Year:  2009        PMID: 19816669     DOI: 10.1007/s00113-009-1683-1

Source DB:  PubMed          Journal:  Unfallchirurg        ISSN: 0177-5537            Impact factor:   1.000


  30 in total

1.  The effects of hypothermia on fibrinogen metabolism and coagulation function in swine.

Authors:  Wenjun Znou Martini
Journal:  Metabolism       Date:  2007-02       Impact factor: 8.694

Review 2.  Interaction between neutrophils and endothelium.

Authors:  M J Elliott; A H Finn
Journal:  Ann Thorac Surg       Date:  1993-12       Impact factor: 4.330

3.  Mild hypothermia improves survival after prolonged, traumatic hemorrhagic shock in pigs.

Authors:  Xianren Wu; Patrick M Kochanek; Kristin Cochran; Ala Nozari; Jeremy Henchir; S William Stezoski; Robert Wagner; Stephen Wisniewski; Samuel A Tisherman
Journal:  J Trauma       Date:  2005-08

4.  Differential effects of lowering culture temperature on mediator release from lipopolysaccharide-stimulated neonatal rat microglia.

Authors:  Soichi Maekawa; Mayuki Aibiki; Qiu-Shang Si; Yoichi Nakamura; Yoichi Shirakawa; Kiyoshi Kataoka
Journal:  Crit Care Med       Date:  2002-12       Impact factor: 7.598

5.  Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage.

Authors:  Y Gundersen; P Vaagenes; A Pharo; E T Valø; P K Opstad
Journal:  Acta Anaesthesiol Scand       Date:  2001-09       Impact factor: 2.105

6.  Hypothermia inhibits human E-selectin transcription.

Authors:  T L Haddix; T H Pohlman; R F Noel; T T Sato; E M Boyle; E D Verrier
Journal:  J Surg Res       Date:  1996-08       Impact factor: 2.192

7.  Hypothermia prolongs activation of NF-kappaB and augments generation of inflammatory cytokines.

Authors:  Karen D Fairchild; Ishwar S Singh; Sandip Patel; Beth E Drysdale; Rose M Viscardi; Lisa Hester; Heather M Lazusky; Jeffrey D Hasday
Journal:  Am J Physiol Cell Physiol       Date:  2004-04-07       Impact factor: 4.249

8.  Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses.

Authors:  Xianren Wu; Jason Stezoski; Peter Safar; Anthony Bauer; Andreas Tuerler; Nicholas Schwarz; Rainer Kentner; Wilhelm Behringer; Patrick M Kochanek; Samuel A Tisherman
Journal:  Crit Care Med       Date:  2003-01       Impact factor: 7.598

9.  Implications of admission hypothermia in trauma patients.

Authors:  S Steinemann; S R Shackford; J W Davis
Journal:  J Trauma       Date:  1990-02

Review 10.  [Management of accidental hypothermia].

Authors:  M Hohlrieder; M Kaufmann; M Moritz; V Wenzel
Journal:  Anaesthesist       Date:  2007-08       Impact factor: 1.041

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  7 in total

1.  Impact of Accidental Hypothermia on Pulmonary Complications in Multiply Injured Patients With Blunt Chest Trauma - A Matched-pair Analysis.

Authors:  Marcel Winkelmann; Jan-Dierk Clausen; Pascal Graeff; Christian Schröter; Christian Zeckey; Sanjay Weber-Spickschen; Philipp Mommsen
Journal:  In Vivo       Date:  2019 Sep-Oct       Impact factor: 2.155

Review 2.  Research progress on combat trauma treatment in cold regions.

Authors:  Hui-Shan Wang; Jin-Song Han
Journal:  Mil Med Res       Date:  2014-05-01

3.  The impact of mild induced hypothermia on the rate of transfusion and the mortality in severely injured patients: a retrospective multi-centre study.

Authors:  Kai Oliver Jensen; Leonhard Held; Andrea Kraus; Frank Hildebrand; Philipp Mommsen; Ladislav Mica; Guido A Wanner; Peter Steiger; Rudolf M Moos; Hans-Peter Simmen; Kai Sprengel
Journal:  Eur J Med Res       Date:  2016-10-06       Impact factor: 2.175

4.  Hypothermia in trauma patients arriving at an emergency department by ambulance in Johannesburg, South Africa: a prospective study.

Authors:  Craig Vincent-Lambert; Cecile May Smith; Lara Nicole Goldstein
Journal:  Pan Afr Med J       Date:  2018-10-23

5.  Hypothermia Induced Impairment of Platelets: Assessment With Multiplate vs. ROTEM-An In Vitro Study.

Authors:  Bernd Wallner; Bettina Schenk; Peter Paal; Markus Falk; Giacomo Strapazzon; Wenjun Z Martini; Hermann Brugger; Dietmar Fries
Journal:  Front Physiol       Date:  2022-03-29       Impact factor: 4.566

Review 6.  Damage control resuscitation: lessons learned.

Authors:  M Giannoudi; P Harwood
Journal:  Eur J Trauma Emerg Surg       Date:  2016-02-04       Impact factor: 3.693

7.  Preventative measures taken against hypothermia in selected Durban hospitals' emergency centres and operating theatres.

Authors:  Matthew James Nel; Timothy Craig Hardcastle
Journal:  Afr J Emerg Med       Date:  2017-05-26
  7 in total

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