Literature DB >> 1981476

Nondisjunction of chromosome 21.

N Takaesu1, P A Jacobs, A Cockwell, R D Blackston, S Freeman, J Nuccio, D M Kurnit, I Uchida, V Freeman, T Hassold.   

Abstract

Chromosome heteromorphisms and restriction fragment length polymorphisms were used to study the origin of the extra chromosome in 54 trisomy 21 conceptuses. The parental origin was determined in 43 cases, with 39 (91%) being maternally and 4 (9%) parentally derived. Analysis of recombination demonstrated the presence of one or two cross-overs in most cases for which sufficient information was available, suggesting that failure to pair/exchange at meiosis I is relatively unimportant in the genesis of trisomy 21.

Mesh：

Year:  1990        PMID： 1981476     DOI： 10.1002/ajmg.1320370735

Source DB:  PubMed          Journal:  Am J Med Genet Suppl        ISSN： 1040-3787


  8 in total

Review 1.  Meiotic origins of maternal age-related aneuploidy.

Authors:  Teresa Chiang; Richard M Schultz; Michael A Lampson
Journal:  Biol Reprod       Date:  2012-01-10       Impact factor: 4.285

2.  Cytogenetic and molecular analysis of a de novo tandem duplication of chromosome 21.

Authors:  J L Blouin; A Aurias; N Créau-Goldberg; F Apiou; C Alcaide-Loridan; A Bruel; M Prieur; J Kraus; J M Delabar; P M Sinet
Journal:  Hum Genet       Date:  1991-12       Impact factor: 4.132

3.  Trisomy 21: association between reduced recombination and nondisjunction.

Authors:  S L Sherman; N Takaesu; S B Freeman; M Grantham; C Phillips; R D Blackston; P A Jacobs; A E Cockwell; V Freeman; I Uchida
Journal:  Am J Hum Genet       Date:  1991-09       Impact factor: 11.025

4.  Nondisjunction of human acrocentric chromosomes: studies of 432 trisomic fetuses and liveborns.

Authors:  M V Zaragoza; P A Jacobs; R S James; P Rogan; S Sherman; T Hassold
Journal:  Hum Genet       Date:  1994-10       Impact factor: 4.132

5.  Investigation of factors associated with paternal nondisjunction of chromosome 21.

Authors:  Tiffany Renee Oliver; Archit Bhise; Eleanor Feingold; Stuart Tinker; Nirupama Masse; Stephanie L Sherman
Journal:  Am J Med Genet A       Date:  2009-08       Impact factor: 2.802

6.  A test of the production line hypothesis of mammalian oogenesis.

Authors:  P E Polani; J A Crolla
Journal:  Hum Genet       Date:  1991-11       Impact factor: 4.132

Review 7.  Trisomy 21 and Assisted Reproductive Technologies: A review.

Authors:  Edgard Sánchez-Pavón; Hector Mendoza; Javier García-Ferreyra
Journal:  JBRA Assist Reprod       Date:  2022-01-17

8.  High Aneuploidy Rates Observed in Embryos Derived from Donated Oocytes are Related to Male Aging and High Percentages of Sperm DNA Fragmentation.

Authors:  Javier García-Ferreyra; Daniel Luna; Lucy Villegas; Rocío Romero; Patricia Zavala; Roly Hilario; Julio Dueñas-Chacón
Journal:  Clin Med Insights Reprod Health       Date:  2015-11-11
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.