BACKGROUND: Although electrocardiographic (ECG) abnormalities are well known in ischemic stroke and subarachnoid hemorrhage, these changes have only rarely been investigated systematically in patients with intracerebral hemorrhage (ICH). The purpose of this study is to investigate the prevalence and type of ECG abnormalities in a consecutive series of ICH patients, and their possible association with pre-defined neurological and radiological parameters. METHODS: The study population consisted of all consecutive patients with non-traumatic, intraparenchymal ICH admitted to the Academic Medical Center (AMC) between January 1, 2007 and October 1, 2007. Baseline information was prospectively registered in the AMC Stroke Register. ECGs obtained within 2 days after the initial hemorrhage were analyzed by one blinded observer. Admission cranial CT scans were re-analyzed by two blinded observers. RESULTS: Thirty-one patients were included. Twenty-five patients (81%) had one or more ECG abnormalities. The most frequently observed ECG abnormality was QTc prolongation (36%), followed by ST-T morphologic changes (23%), sinus bradycardia (16%), and inverted T wave (16%). No patient was initially misdiagnosed for having myocardial ischemia. QTc prolongation was associated with ICH involvement of the insular cortex [OR 10.9 (95% CI 1.0-114.6)] and presence of intraventricular blood and hydrocephalus on admission CT scan [OR 10.8 (95% CI 1.6-70.9)]. CONCLUSIONS: In ICH patients ECG abnormalities are common. QTc prolongation seems associated with insular cortex involvement, with the presence of intraventricular blood, and with hydrocephalus. A larger cohort of continuously monitored ICH patients is necessary to investigate whether these ECG abnormalities are associated with poor outcome or death.
BACKGROUND: Although electrocardiographic (ECG) abnormalities are well known in ischemic stroke and subarachnoid hemorrhage, these changes have only rarely been investigated systematically in patients with intracerebral hemorrhage (ICH). The purpose of this study is to investigate the prevalence and type of ECG abnormalities in a consecutive series of ICHpatients, and their possible association with pre-defined neurological and radiological parameters. METHODS: The study population consisted of all consecutive patients with non-traumatic, intraparenchymal ICH admitted to the Academic Medical Center (AMC) between January 1, 2007 and October 1, 2007. Baseline information was prospectively registered in the AMC Stroke Register. ECGs obtained within 2 days after the initial hemorrhage were analyzed by one blinded observer. Admission cranial CT scans were re-analyzed by two blinded observers. RESULTS: Thirty-one patients were included. Twenty-five patients (81%) had one or more ECG abnormalities. The most frequently observed ECG abnormality was QTc prolongation (36%), followed by ST-T morphologic changes (23%), sinus bradycardia (16%), and inverted T wave (16%). No patient was initially misdiagnosed for having myocardial ischemia. QTc prolongation was associated with ICH involvement of the insular cortex [OR 10.9 (95% CI 1.0-114.6)] and presence of intraventricular blood and hydrocephalus on admission CT scan [OR 10.8 (95% CI 1.6-70.9)]. CONCLUSIONS: In ICHpatients ECG abnormalities are common. QTc prolongation seems associated with insular cortex involvement, with the presence of intraventricular blood, and with hydrocephalus. A larger cohort of continuously monitored ICHpatients is necessary to investigate whether these ECG abnormalities are associated with poor outcome or death.
Authors: Boby V Maramattom; Edward M Manno; Jimmy R Fulgham; Allan S Jaffe; Eelco F M Wijdicks Journal: Mayo Clin Proc Date: 2006-02 Impact factor: 7.616
Authors: Clara Hjalmarsson; Lennart Bergfeldt; Lena Bokemark; Karin Manhem; Björn Andersson Journal: Ann Noninvasive Electrocardiol Date: 2013-05-03 Impact factor: 1.468
Authors: Abiodun M Adeoye; Okechukwu S Ogah; Bruce Ovbiagele; Rufus Akinyemi; Vincent Shidali; Francis Agyekum; Akinyemi Aje; Oladimeji Adebayo; Joshua O Akinyemi; Philip Kolo; Lambert Tetteh Appiah; Henry Iheonye; Uwanuruochi Kelechukwu; Amusa Ganiyu; Taiwo O Olunuga; Onoja Akpa; Ojo Olakanmi Olagoke; Fred Stephen Sarfo; Kolawole Wahab; Samuel Olowookere; Adekunle Fakunle; Albert Akpalu; Philip B Adebayo; Kwadwo Nkromah; Joseph Yaria; Philip Ibinaiye; Godwin Ogbole; Aridegbe Olumayowa; Sulaiman Lakoh; Benedict Calys-Tagoe; Paul Olowoyo; Chukwuonye Innocent; Hemant K Tiwari; Donna Arnett; Osaigbovo Godwin; Bisi Ayotunde; Josephine Akpalu; Okeke Obiora; Odo Joseph; Adeleye Omisore; Carolyn Jenkins; Daniel Lackland; Lukman Owolabi; Suleiman Isah; Abdu H Dambatta; Morenikeji Komolafe; Andrew Bock-Oruma; Ezinne Sylvia Melikam; Lucius Chidiebere Imoh; Taofiki Sunmonu; Mulugeta Gebregziabher; Oluyemisi Olabisi; Kevin Armstrong; Ugochukwu U Onyeonoro; Emmanuel Sanya; Atinuke M Agunloye; Luqman Ogunjimi; Oyedunni Arulogun; Temitope H Farombi; Olugbo Obiabo; Reginald Obiako; Mayowa Owolabi Journal: Glob Heart Date: 2017-03-14